Listando por materia "MNK1"
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Overcoming Paradoxical Kinase Priming by a Novel MNK1 Inhibitor
(Journal of Medicinal Chemistry, 2022, 65(8), 6070-6087, 2022-04-28)Targeting the kinases MNK1 and MNK2 has emerged as a valuable strategy in oncology. However, most of the advanced inhibitors are acting in an adenosine triphosphate (ATP)-competitive mode, precluding ...