Now showing items 1-4 of 4

    • Development of green/red-absorbing chromophores based on a coumarin scaffold that are useful as caging groups 

      Nonell, Santi; Gandioso, Albert; Contreras, Sara; Melnyk, Ivanna; Oliva, Javier; Velasco Castrillo, Dolores; Garcia Amorós, Jaume; Marchán Sancho, Vicente (Journal of Organic Chemistry. Vol.82, n.10 (2017), p.5398-5408, 2017-05)
      We report the design, synthesis, and spectroscopic characterization of a series of push–pull chromophores based on a novel coumarin scaffold in which the carbonyl of the lactone function of the original ...
    • Exploring Structure–Activity Relationships in Photodynamic Therapy Anticancer Agents Based on Ir(III)-COUPY Conjugates 

      Rovira, Anna; Ortega Forte, Enrique; Hally, Cormac; Jordà Redondo, Mireia; Abad-Montero, Diego; Vigueras, Gloria; Martínez, Jesús I.; Bosch, Manel; Nonell, Santi; Ruiz, José; Marchán, Vicente (Journal of Medicinal Chemistry 2023, 66 (12), 2023-06-22)
      Photodynamic therapy holds great promise as a non-invasive anticancer tool against drug-resistant cancers. However, highly effective, non-toxic, and reliable photosensitizers with operability under ...
    • Innovative light sources for phototherapy 

      Romano, Giovanni; Insero, Giacomo; Nonell, Santi; Fusi, Franco (Biomolecular Concepts 2022, 13(1), 256-271, 2022)
      The use of light for therapeutic purposes dates back to ancient Egypt, where the sun itself was an innovative source, probably used for the first time to heal skin diseases. Since then, technical ...
    • On the mechanism of Candida tropicalis biofilm reduction by the combined action of naturally-occurring anthraquinones and blue light 

      Nonell, Santi; Bresolí Obach, Roger; Agut Bonsfills, Montserrat; Marioni, Juliana; Comini, Laura R.; Cabrera, José L.; Paraje, María G.; Núñez Montoya, Susana C. (PLoS ONE. Vol.12, n.7 (2017), e0181517, 2017-07)
      The photoprocesses involved in the photo-induced Candida tropicalis biofilm reduction by two natural anthraquinones (AQs), rubiadin (1) and rubiadin-1-methyl ether (2), were examined. Production of ...