Browsing by Subject "Inhibitors"
Now showing items 1-2 of 2
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De-Novo Design of pre-miR-21 Maturation Inhibitors: Synthesis and Activity Assessment
(Chemistry - A European Journal 2023, 29(40),e202300825, 2023-07-14)Targeting RNA with small molecules is a major challenge of current medicinal chemistry, and the identification and design of original scaffolds able to selectively interact with an RNA target remains ... -
Nitrogen positional scanning in tetramines active against HIV-1 as potential CXCR4 inhibitors
(Organic & Biomolecular Chemistry. Vol.14, n.4 (2016), p.1455-1472, 2015-12)The paradigm, derived from bicyclams and other cyclams, by which it is necessary to use the p-phenylene moiety as the central core in order to achieve high HIV-1 antiviral activities has been reexamined ...