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Browsing by Subject "Dopamina"

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    • Pharmacogenetic influences on the response to pharmacological treatment in autism spectrum disorders 

      Hervas, Amaia; Serra-Llovich, Alexandre; Rueda, Isabel; Targa, Irene; Guijarro, Silvina; Bigorra, Aitana; Cancino, Martha; Bote, Valentin; Cárcel, María; Amasi-Hartoonian, Nare; Hernández Hernández, Marta; Arranz, Maria J (Journal of Translational Genetics and Genomics, 2021, 5:278-287, 2021-07)
      Aim: About a third of patients with autism spectrum disorder (ASD) receive pharmacological treatment for comorbid symptoms. However, 30%-50% do not respond adequately and/or present severe and long-lasting ...

    • Role of amino terminal substitutions in the pharmacological, rewarding and psychostimulant profiles of novel synthetic cathinones 

      Duart-Castells, L.; Nadal Gratacós, Núria; Muralter, M.; Puster, B.; Berzosa, Xavier; Estrada-Tejedor, Roger; Niello, M.; Bhat, S.; Pubill, David; Camarasa, Jordi; Sitte, H. H.; Fonseca, David; López-Arnau, Raúl (Neuropharmacology, 2021-03-15)
      The emergence of new synthetic cathinones continues to be a matter of public health concern. In fact, they are quickly replaced by new structurally related alternatives. The main goal of the present ...

    • Unveiling the potential abuse liability of α-D2PV: A novel α-carbon phenyl-substituted synthetic cathinone 

      Nadal-Gratacós, Núria; Mata, Sandra; Puigseslloses, Pol; De Macedo, Morgane; Lardeux, Virginie; Pain, Stephanie; Wang, Fu-Hua; Källsten, Liselott; Pubill, David; Berzosa, Xavier; Kehr, Jan; Solinas, Marcello; Camarasa, Jordi; Escubedo, Elena; López-Arnau, Raúl (Neuropharmacology 2025, 272, 2025-07-01)
      Synthetic cathinones are emerging psychoactive substances designed to mimic the effects of classical psychostimulants. Among them, α-D2PV, a novel pyrrolidine-containing cathinone characterized by a ...