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Browsing by Subject "DLBCL"

Now showing items 1-2 of 2

    • Applying Molecular Modeling to the Design of Innovative, Non-Symmetrical CXCR4 Inhibitors with Potent Anticancer Activity 

      Martínez-Asensio, Miquel; Sàrrias, Lluís; Gorjón de Pablo, Gema; Fernández-Serrano, Miranda; Camaló Vila, Judith; Puig de la Bellacasa, Raimon; Teixidó, Jordi; Roué, Gaël; Borrell, Jose I.; Estrada-Tejedor, Roger; Gibert Bosch, Albert (International Journal of Molecular Sciences. 2024;25(17):9446, 2024-08-28)
      The identification of new compounds with potential activity against CXC chemokine receptor type 4 (CXCR4) has been broadly studied, implying several chemical families, particularly AMD3100 derivatives. ...

    • STAT6 mutations enriched at diffuse large B-cell lymphoma relapse reshape the tumor microenvironment 

      Benoit, Alexandre; Abraham, Madelyn; Li, Sheena; Kim, John; Estrada-Tejedor, Roger; Bakadlag, Rowa; Subramaniam, Nivetha; Makhani, Kiran; Guilbert, Cynthia (International Journal of Hematology. 2024;119:275–290, 2024-01-29)
      Diffuse large B-cell lymphoma (DLBCL) relapses in approximately 40% of patients following frontline therapy. We reported that STAT6D419 mutations are enriched in relapsed/refractory DLBCL (rrDLBCL) ...