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Browsing by Subject "Cancer"

Now showing items 1-4 of 4

    • Engineered microtissues for the bystander therapy against cancer 

      Blanco-Fernandez, Barbara; Cano-Torres, Irene; Garrido, Cristina; Rubí-Sans, Gerard; Sánchez-Cid, Lourdes; Guerra-Rebollo, Marta; Rubio, Nuria; Blanco, Jeronimo; Pérez-Amodio, Soledad; Mateos-Timoneda, Miguel Ángel; Engel, Elisabeth (Materials Science and Engineering C, 2021-01-13)
      Thymidine kinase expressing human adipose mesenchymal stem cells (TK-hAMSCs) in combination with ganciclovir (GCV) are an effective platform for antitumor bystander therapy in mice models. However, this ...

    • Porficenos para la fotoquimioterapia del cáncer y otras aplicaciones biomédicas 

      Nonell, Santi; Sánchez-García, David; Borrell, Jose I.; Teixidó, Jordi; Arad, Ofir; Gavaldá, Ana; Rey, Óscar; Rubio, Noemi; Cañete, Magdalena; Juarranz, Ángeles; Villanueva, Ángeles; Stockert, Juan Carlos; Díaz Jiménez, Pablo J. (Afinidad. Vol.59, n.500 (2002), p.343-356, 2002)
      La terapia fotodinámica (PDT) o fotoquimioterapia del cáncer es una modalidad terapéutica que consiste en la aplicación de compuestos fotosensibilizadores que se acumulan preferentemente en tejidos ...

    • Recent advances in the pharmacological targeting of ubiquitin-regulating enzymes in cancer 

      Montagut, Ana Maria; Armengol, Marc; Gorjón de Pablo, Gema; Estrada-Tejedor, Roger; Borrell, Jose I.; Roué, Gaël (Seminars in Cell & Developmental Biology 2022, 132, 213-229, 2022-12)
      As a post-translational modification that has pivotal roles in protein degradation, ubiquitination ensures that intracellular proteins act in a precise spatial and temporal manner to regulate diversified ...

    • Three-dimensional tumor-stroma co-culture system development using self-assembling peptide scaffolds 

      Semino, Carlos; Betriu, C. (Afinidad. Vol.76, n.587 (2019), p.163-170, 2019-07)
      Cancer research has traditionally relied on 2D cell culture, focusing mainly on cancer cells and its disrupted genetics. However, tumors have been accepted as complex tissues, and as such, they need ...