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    • A machine learning approach to predict cellular uptake of pBAE polyplexes 

      Loecher, Aparna; Bruyns-Haylett, Michael; Ballester, Pedro J.; Borrós i Gómez, Salvador; Oliva, Núria (Biomaterials Science 2023, 12(17), 5697-6002, 2023-09)
      The delivery of genetic material (DNA and RNA) to cells can cure a wide range of diseases but is limited by the delivery efficiency of the carrier system. Poly β-amino esters (pBAEs) are promising ...

    • Simple generation of human induced pluripotent stem cells using poly-β-amino esters as the non-viral gene delivery system 

      Borrós i Gómez, Salvador; Ramos Pérez, Víctor; Gutiérrez, Jordán; Izpisúa Belmonte, J. C.; Montserrat, Núria; Garreta, Elena; González, Federico; Eguizábal, Cristina (Journal of Biological Chemistry. Vol.286,n.14 (2011),p.12417-12428, 2011-04)
      Reprogramming of somatic cells to induced pluripotent stem (iPS) cells can be achieved by the delivery of a combination of transcription factors, including Oct4, Sox2, Klf4, and c-Myc. Retroviral and ...