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    • Chelating properties of tripeptide-9 citrulline 

      Abellà, Jordi (Abellà i Iglesias); Colominas Fuster, Sergi; Viladot, J. L.; Fernández-Botello, A.; Delgado, R. (Afinidad. Vol.69, n.560 (2012), p.245-250, 2012-10)
      Tripeptide-9 Citrulline (INCI name) is a peptide with skin care properties, used for cosmetic applications. In order to elucidate its mechanism of action in the chemical pathways that involve metal ions, ...
    • Culture and differentiation of human hair follicle dermal papilla cells in a soft 3D self-assembling peptide scaffold 

      Semino, Carlos; Betriu, Nausika; Jarrosson-Moral, Claire (Biomolecules. Vol.10, n.5 (2020), 684, 2020-05)
      Hair follicle dermal papilla cells (HFDPC) are a specialized cell population located in the bulge of the hair follicle with unique characteristics such as aggregative behavior and the ability to induce ...
    • Increased Stiffness Downregulates Focal Adhesion Kinase Expression in Pancreatic Cancer Cells Cultured in 3D Self-Assembling Peptide Scaffolds 

      Betriu, Nausika; Andreeva, Anna; Alonso, Anna; Semino, Carlos (Biomedicines 2022, 10(8), 1835, 2022-08)
      The focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that participates in integrin-mediated signal transduction and contributes to different biological processes, such as cell migration, ...
    • The Masking Game: Design of Activatable Antibodies and Mimetics for Selective Therapeutics and Cell Control 

      Lucchi, Roberta; Bentanachs, Jordi; Oller Salvia, Benjamí (ACS Central Science, 2021-04-26)
      The high selectivity and affinity of antibody binding havemade antibodies all-pervasive tools in therapy, diagnosis, and basic science.A plethora of chemogenetic approaches has been devised to makeantibodies ...
    • Three-dimensional tumor-stroma co-culture system development using self-assembling peptide scaffolds 

      Semino, Carlos; Betriu, C. (Afinidad. Vol.76, n.587 (2019), p.163-170, 2019-07)
      Cancer research has traditionally relied on 2D cell culture, focusing mainly on cancer cells and its disrupted genetics. However, tumors have been accepted as complex tissues, and as such, they need ...
    • Versatile Supramolecular Complex for Targeted Antimicrobial Photodynamic Inactivation 

      Mussini, Andrea; Uriati, Eleonora; Hally, Cormac; Nonell, Santi; Bianchini, Paolo; Diaspro, Alberto; Pongolini, Stefano; Delcanale, Pietro; Abbruzzetti, Stefania; Viappiani, Cristiano (Bioconjugate Chemistry 2022, 33(4), 666–676, 2022-04-20)
      We report the development of a supramolecular structure endowed with photosensitizing properties and targeting capability for antimicrobial photodynamic inactivation. Our synthetic strategy uses the ...
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