Listando por materia "Malària"
Mostrando ítems 1-2 de 2
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Plasmodium falciparum apicomplexan-specific glucosamine-6-phosphate n-acetyltransferase is key for amino sugar metabolism and asexual blood stage development
(Molecular Biology and Physiology. Vol.11, n.5 (2020), e02045-20, 2020-10)ABSTRACT UDP-N-acetylglucosamine (UDP-GlcNAc), the main product of the hexosamine biosynthetic pathway, is an important metabolite in protozoan parasites since its sugar moiety is incorporated into ... -
Zwitterionic self-assembled nanoparticles as carriers for Plasmodium targeting in malaria oral treatment
(Journal of Controlled Release. Vol.331, p.364-375, 2021-03-10)The current decline in antimalarial drug efficacy due to the evolution of resistant Plasmodium strains calls for new strategies capable of improving the bioavailability of antimalarials, especially of ...