Listando por materia "Fetge"
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Glycogenin is dispensable for normal liver glycogen metabolism and body glucose homeostasis
(International Journal of Biological Macromolecules 2025, 291, 139084, 2025-02)Glycogen is a glucose-storage polysaccharide molecule present in animals, fungi and bacteria. The enzyme glycogenin can self-glycosylate, forming an oligosaccharide chain that primes glycogen synthesis. ... -
Hepatic overexpression of protein targeting to glycogen attenuates obesity and improves hyperglycemia in db/db mice
(Frontiers in Endocrinology, 2022, 13, 969924, 2022)Increased liver glycogen content has been shown to reduce food intake, attenuate obesity, and improve glucose tolerance in a mouse model of high-fat diet (HFD)-induced obesity. Here we studied the ... -
Metabolic dysfunction-associated steatotic liver disease in severe obesity and concordance between Invasive (Biopsy) and noninvasive (OWLiver®) diagnoses
(Obesity Facts, 2024, 17(5): 473-482, 2024-06)Introduction: Nonalcoholic fatty liver disease (NAFLD), now termed metabolic dysfunction-associated steatotic liver disease (MASLD), is an escalating health concern linked to obesity and type 2 diabetes. ...