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Listando por materia "Antipsicòtics"

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    • Clinical utility and implementation of pharmacogenomics for the personalisation of antipsychotic treatments 

      Hernández Hernández, Marta; Cullell, Natalia; Cendros, Marc; Serra-Llovich, Alexandre; Arranz, Maria J (Pharmaceutics, 2024, 16(2): 244, 2024-02)
      Decades of pharmacogenetic research have revealed genetic biomarkers of clinical response to antipsychotics. Genetic variants in antipsychotic targets, dopamine and serotonin receptors in particular, ...

    • Pharmacogenetic influences on the response to pharmacological treatment in autism spectrum disorders 

      Hervas, Amaia; Serra-Llovich, Alexandre; Rueda, Isabel; Targa, Irene; Guijarro, Silvina; Bigorra, Aitana; Cancino, Martha; Bote, Valentin; Cárcel, María; Amasi-Hartoonian, Nare; Hernández Hernández, Marta; Arranz, Maria J (Journal of Translational Genetics and Genomics, 2021, 5:278-287, 2021-07)
      Aim: About a third of patients with autism spectrum disorder (ASD) receive pharmacological treatment for comorbid symptoms. However, 30%-50% do not respond adequately and/or present severe and long-lasting ...

    • Pharmacogenetic interventions improve the clinical outcome of treatment-resistant autistic spectrum disorder sufferers 

      Arranz, Maria J; Salazar, Juliana; Bote, Valentin; Artigas-Baleri, Alícia; Serra-Llovich, Alexandre; Triviño, Emma; Roige, Jordi; Lombardia, Carlos; Cancino, Martha; Hernández Hernández, Marta; Cendros, Marc; Duran-Tauleria, Enric; Maraver, Natalia; Hervas, Amaia (Pharmaceutics, 2022, 14 (5), 999, 2022-05)
      BACKGROUND: Autistic spectrum disorders (ASD) are severe neurodevelopmental alterations characterised by deficits in social communication and repetitive and restricted behaviours. About a third of ...

    • Pharmacogenetics of antipsychotics: clinical utility and implementation 

      Arranz, Maria J; Salazar, Juliana; Hernández Hernández, Marta (Behavioural Brain Research, 2021, vol. 401, 113058, 2020-12)
      Decades of research have produced extensive evidence of the contribution of genetic factors to the efficacy and toxicity of antipsychotics. Numerous genetic variants in genes controlling drug availability ...