Listando por materia "Aleatorització Mendeliana"
Mostrando ítems 1-7 de 7
-
Body mass index and subfertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study
(Human Reproduction, 2021, 36(12), 3141-3151, 2021-10)STUDY QUESTION What is the association between BMI and subfertility? SUMMARY ANSWER We observed a J-shaped relationship between BMI and subfertility in both sexes, when using both a standard ... -
Cardiovascular disease risk factors and infertility: multivariable analyses and one-sample Mendelian randomization analyses in the Trøndelag Health Study
(Human Reproduction Open, 2024, 2024 (3), hoae033, 2024-05)STUDY QUESTION Are cardiovascular disease (CVD) risk factors causally associated with higher risk of infertility among women and men? SUMMARY ANSWER We found evidence to support a causal relationship ... -
High-density lipoprotein characteristics and coronary artery disease: a Mendelian randomization study
(Metabolism Clinical and Experimental, 2020, 112: 154351, 2020-09)Background To assess whether genetically determined quantitative and qualitative HDL characteristics were independently associated with coronary artery disease (CAD). Methods We designed a two-sample ... -
Impaired glucose tolerance and cardiovascular risk factors in relation to infertility: a Mendelian randomization analysis in the Norwegian Mother, Father, and Child Cohort Study
(Human Reproduction, 2024, 39(2), 436-441, 2023-11)STUDY QUESTION Are impaired glucose tolerance (as measured by fasting glucose, glycated hemoglobin, and fasting insulin) and cardiovascular disease risk (as measured by low-density lipoprotein cholesterol, ... -
Prospective and Mendelian randomization analyses on the association of circulating fatty acid binding protein 4 (FABP‑4) and risk of colorectal cancer
(BMC Medicine, 2023, 21: 391, 2023-10)Background Fatty acid binding protein 4 (FABP-4) is a lipid-binding adipokine upregulated in obesity, which may facilitate fatty acid supply for tumor growth and promote insulin resistance and inflammation ... -
Smoking and infertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study
(Fertility and Sterility, 2022, 118(1): 180-190, 2022-07)Objective To investigate the association between smoking and infertility. Design Prospective study. Setting Nationwide cohort. Patients 28,606 women and 27,096 men with questionnaire and genotype ... -
Telomere length in relation to fecundability and use of assisted reproductive technologies: the Norwegian mother, father, and child cohort study
(BMC Medicine, 2024, 22: 580, 2024-12)Background Telomere length (TL) has been reported to be associated with conditions such as endometriosis and polycystic ovary syndrome, with some studies finding associations with shorter TL and others ...