Browsing by Subject "Drug delivery"
Now showing items 1-9 of 9
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An Orthogonally Clickable and Stimuli-Responsive Poly(β-amino ester) for the Co-delivery of Doxorubicin and BCL-2 siRNA
(ACS Applied Polymer Materials 2025, 7 (11), 7013–7024, 2025-06-13)A potent drug delivery system (DDS) based on poly(β-amino ester)s (pBAEs) to tackle multidrug resistance (MDR) in lung cancer by codelivering siRNA targeting antiapoptotic BCL-2 and doxorubicin (DOX) ... -
Extracellular vesicles and their current role in cancer immunotherapy
(Cancers, 2021-05-10)Extracellular vesicles (EVs) are natural particles formed by the lipid bilayer and released from almost all cell types to the extracellular environment both under physiological conditions and in presence ... -
Nanopartículas de sílice: preparación y aplicaciones en biomedicina
(Afinidad. Vol.71, n.565 (2014), p.20-31, 2014-01)Actualmente, un importante número de avances científicos se fundamentan en la utilización de nanopartículas cómo superficies de actuación, vehículos de transporte, en procesos relacionados con aplicaciones ... -
New Trends in Brain Shuttle Peptides
(Molecular Pharmaceutics 2025, 22, 3, 1100–1109, 2025-03-03)The pharmacological treatment of central nervous system diseases faces significant challenges due to the presence of the blood–brain barrier (BBB). This barrier naturally protects the brain and prevents ... -
PET Imaging of Self-Assembled 18F-Labelled Pd2L4 Metallacages for Anticancer Drug Delivery
(Chemistry – A European Journal 2023, 29(3), e202202604, 2023-01-12)To advance the design of self-assembled metallosupramolecular architectures as new generation theranostic agents, the synthesis of 18F-labelled [Pd2L4]4+ metallacages is reported. Different spectroscopic ... -
Photosensitive EGFR-Targeted Nanocarriers for Combined Photodynamic and Local Chemotherapy
(Pharmaceutics 2022, 14(2), 405, 2022-02)The major limitation of any cancer therapy lies in the difficulty of precisely controlling the localization of the drug in the tumor cells. To improve this drawback, our study explores the use of ... -
Photosensitizing proteins for antibacterial photodynamic inactivation
(Translational Biophotonics. Vol.2, n.1-2 (2020) e201900031, 2020-05)We review recent applications of water‐soluble proteins as carriers for photosensitizing molecules in antimicrobial photodynamic therapy (aPDT). The low water solubility of photosensitizers and their ... -
Preparation and applications of organo-silica hybrid mesoporous silica nanoparticles for the co-delivery of drugs and nucleic acids
(Nanomaterials. Vol.10, n.12 (2020), 2466, 2020-12)Combination therapies rely on the administration of more than one drug, with independent mechanisms of action, aiming to enhance the efficiency of the treatment. For an optimal performance, the ... -
Zwitterionic self-assembled nanoparticles as carriers for Plasmodium targeting in malaria oral treatment
(Journal of Controlled Release. Vol.331, p.364-375, 2021-03-10)The current decline in antimalarial drug efficacy due to the evolution of resistant Plasmodium strains calls for new strategies capable of improving the bioavailability of antimalarials, especially of ...