Visualitzant per matèria "Self-assembling peptides"
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Culture and differentiation of human hair follicle dermal papilla cells in a soft 3D self-assembling peptide scaffold
(Biomolecules. Vol.10, n.5 (2020), 684, 2020-05)Hair follicle dermal papilla cells (HFDPC) are a specialized cell population located in the bulge of the hair follicle with unique characteristics such as aggregative behavior and the ability to induce ... -
Erlotinib Promotes Ligand-Induced EGFR Degradation in 3D but Not 2D Cultures of Pancreatic Ductal Adenocarcinoma Cells
(Cancers, 2021-09-07)The epithelial growth factor receptor (EGFR) is a tyrosine kinase receptor that participates in many biological processes such as cell proliferation. In addition, EGFR is overexpressed in many epithelial ... -
Increased Stiffness Downregulates Focal Adhesion Kinase Expression in Pancreatic Cancer Cells Cultured in 3D Self-Assembling Peptide Scaffolds
(Biomedicines 2022, 10(8), 1835, 2022-08)The focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that participates in integrin-mediated signal transduction and contributes to different biological processes, such as cell migration, ... -
Three-dimensional tumor-stroma co-culture system development using self-assembling peptide scaffolds
(Afinidad. Vol.76, n.587 (2019), p.163-170, 2019-07)Cancer research has traditionally relied on 2D cell culture, focusing mainly on cancer cells and its disrupted genetics. However, tumors have been accepted as complex tissues, and as such, they need ... -
β-Sheet to Random Coil Transition in Self-Assembling Peptide Scaffolds Promotes Proteolytic Degradation
(Biomolecules 2022, 12(3), 411, 2022-03)One of the most desirable properties that biomaterials designed for tissue engineering or drug delivery applications should fulfill is biodegradation and resorption without toxicity. Therefore, there ...