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Sex- and site-specific associations of circulating lipocalin 2 and incident colorectal cancer: Results from the EPIC cohort

Reichmann, Robin; Nimptsch, Katharina; Pischon, Tobias; Gunter, Marc J.; Jenab, Mazda; Eriksen, Anne Kirstine; Tjonneland, Anne; Janke, Jürgen; Katzke, Verena Andrea; Kaaks, Rudolf; Schulze, Matthias B.; Eichelmann, Fabian; Masala, Giovanna; Sieri, Sabina; Pasanisi, Fabrizio; Tumino, Rosario; Giraudo, Maria Teresa; Rothwell, Joseph A.; Severi, Gianluca; Jakszyn, Paula; Sanchez-Perez, Maria Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Guevara, Marcela; Van Guelpen, Bethany; Aglago, Elom K; Heath, Alicia K.; Smith-Byrne, Karl; Weiderpass, Elisabete; Aleksandrova, Krasimira (International Journal of Cancer, 2025, 156(5): 930-942, 2024-11)

Experimental research has uncovered lipocalin 2 (LCN2) as a novel biomarker implicated in the modulation of intestinal inflammation, metabolic homeostasis, and colon carcinogenesis. However, evidence ...