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Current progress in bionanomaterials to modulate the epigenome
(Biomaterials Science 2022, 18, 5021-5358, 2022)Recent advances in genomics during the 1990s have made it possible to study and identify genetic and epigenetic responses of cells and tissues to various drugs and environmental factors. This has ... -
In silico discovery of substituted pyrido[2,3-d]pyrimidines and pentamidine-like compounds with biological activity in myotonic dystrophy models
(PLoS ONE. Vol.12, n.6 (2017), e0178931, 2017-06)Myotonic dystrophy type 1 (DM1) is a rare multisystemic disorder associated with an expansion of CUG repeats in mutant DMPK (dystrophia myotonica protein kinase) transcripts; the main effect of these ...