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    • Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator 

      Nonell, Santi; Bresolí Obach, Roger; Font Inglès, Joan; López-Cano, Marc; Notartomaso, Serena; Scarselli, Pamela; Di Pietro, Paola; Battaglia, Giuseppe; Malhaire, Fanny; Rovira, Xavier; Catena, Juanlo; Giraldo, Jesús; Pin, Jean-Philippe; Fernández-Dueñas, Víctor; Goudet, Cyril; Nicoletti, Ferdinando; Llebaria, Amadeu; Ciruela, Francisco (eLIFE. Vol.6 (2017), e23545, 2017-04)
      Light-operated drugs constitute a major target in drug discovery, since they may provide spatiotemporal resolution for the treatment of complex diseases (i.e. chronic pain). JF-NP-26 is an inactive ...