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CRISPR/Cas9-Mediated Knockin Application in Cell Therapy: A Non-viral Procedure for Bystander Treatment of Glioma in Mice
(Molecular Therapy: Nucleic Acids, 2017-07-26)The use of non-viral procedures, together with CRISPR/Cas9 genome-editing technology, allows the insertion of single-copy therapeutic genes at pre-determined genomic sites, overcoming safety limitations ... -
Current progress in bionanomaterials to modulate the epigenome
(Biomaterials Science 2022, 18, 5021-5358, 2022)Recent advances in genomics during the 1990s have made it possible to study and identify genetic and epigenetic responses of cells and tissues to various drugs and environmental factors. This has ...