Visualitzant per matèria "Cèl·lules"
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Application of flow cytometry analysis to elucidate the impact of scale-down conditions in Escherichia coli cultivations
(Afinidad. Vol.73, n.573 (2016), p.7-15, 2016-01)In homogeneities appear in large-scale fed-batch bioprocesses; especially when the distribution of the feeding solution and of the oxygen is uneven. In order to study the consequences of these heterogenic ... -
Complex pBAE Nanoparticle Cell Trafficking: Tracking Both Position and Composition Using Super Resolution Microscopy
(ChemMedChem 2022, 17(13), e202100633, 2022)Nanomedicine emerged some decades ago with the hope to be the solution for most unmet medical needs. However, tracking materials at nanoscale is challenging to their reduced size, below the resolution ... -
Dynamical landscapes of cell fate decisions
(Interface Focus 2022, 12(4), 2022-08)The generation of cellular diversity during development involves differentiating cells transitioning between discrete cell states. In the 1940s, the developmental biologist Conrad Waddington introduced ... -
Exploring Structure–Activity Relationships in Photodynamic Therapy Anticancer Agents Based on Ir(III)-COUPY Conjugates
(Journal of Medicinal Chemistry 2023, 66 (12), 2023-06-22)Photodynamic therapy holds great promise as a non-invasive anticancer tool against drug-resistant cancers. However, highly effective, non-toxic, and reliable photosensitizers with operability under ... -
Structural implications of the DFD-in domain in computer-aided molecular design of MAP kinase interacting kinase 2 inhibitors
(Afinidad. Vol.74, n.578 (2017), p.83-89, 2017-04)Protein translation is a key process on cell development and proliferation that is often deregulated in cancer. MAP kinase interacting kinases 1 and 2 (Mnk1/2) play a pivotal role in regulating the ...