Visualitzant per matèria "Antipsicòtics"
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Adherence to a Mediterranean diet and leisure-time physical activity are associated with reduced initiation of antidepressant, anxiolytic, antipsychotic and antiseizure drug use in older adults: a cohort study
(Age and ageing, 2025, 54(4): afaf088, 2025-04)Background We explored how adherence to the Mediterranean diet (MedDiet) and leisure-time physical activity (LTPA) impact psychoactive medication use in older adults. Methods We assessed the ... -
Clinical utility and implementation of pharmacogenomics for the personalisation of antipsychotic treatments
(Pharmaceutics, 2024, 16(2): 244, 2024-02)Decades of pharmacogenetic research have revealed genetic biomarkers of clinical response to antipsychotics. Genetic variants in antipsychotic targets, dopamine and serotonin receptors in particular, ... -
Pharmacogenetic influences on the response to pharmacological treatment in autism spectrum disorders
(Journal of Translational Genetics and Genomics, 2021, 5:278-287, 2021-07)Aim: About a third of patients with autism spectrum disorder (ASD) receive pharmacological treatment for comorbid symptoms. However, 30%-50% do not respond adequately and/or present severe and long-lasting ... -
Pharmacogenetic interventions improve the clinical outcome of treatment-resistant autistic spectrum disorder sufferers
(Pharmaceutics, 2022, 14 (5), 999, 2022-05)BACKGROUND: Autistic spectrum disorders (ASD) are severe neurodevelopmental alterations characterised by deficits in social communication and repetitive and restricted behaviours. About a third of ... -
Pharmacogenetics of antipsychotics: clinical utility and implementation
(Behavioural Brain Research, 2021, vol. 401, 113058, 2020-12)Decades of research have produced extensive evidence of the contribution of genetic factors to the efficacy and toxicity of antipsychotics. Numerous genetic variants in genes controlling drug availability ...