• A near-infrared light-activatable Ru(ii)-coumarin photosensitizer active under hypoxic conditions 

      Ortega Forte, Enrique; Rovira, Anna; López Corrales, Marta; Hernández García, Alba; Ballester, Francisco José; Izquierdo García, Eduardo; Jordà Redondo, Mireia; Bosch, Manel; Nonell, Santi; Santana, María Dolores; Ruiz, José; Marchán, Vicente; Gasser, Gilles (Chemical Space 2023, 15(26), 2023-07-14)
      Photodynamic therapy (PDT) represents a promising approach for cancer treatment. However, the oxygen dependency of PDT to generate reactive oxygen species (ROS) hampers its therapeutic efficacy, especially ...
    • Mitochondria-Targeted COUPY Photocages: Synthesis and Visible-Light Photoactivation in Living Cells 

      López Corrales, Marta; Rovira, Anna; Gandioso, Albert; Nonell, Santi; Bosch, Manel; Marchán, Vicente (The Journal of Organic Chemistry 2023, 88, 7128-7140, 2023-06-02)
      Releasing bioactive molecules in specific subcellular locations from the corresponding caged precursors offers great potential in photopharmacology, especially when using biologically compatible visible ...