Browsing by Author "Fahim, Arjang"

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    • Stochastic modeling reveals kinetic heterogeneity in post-replication DNA methylation 

      Busto-Moner, Luis; Read, Elizabeth L.; Morival, Julien; Ren, Honglei; Fahim, Arjang; Reitz, Zachary; Downing, Timothy L. (PLoS Computational Biology. Vol. 16, n.4 (2020), e1007195, 2020-04)
      DNA methylation is a heritable epigenetic modification that plays an essential role in mammalian development. Genomic methylation patterns are dynamically maintained, with DNA methyltransferases mediating ...