Browsing by Author "Faijes, Magda"
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Glycosidases and glycosynthases in enzymatic synthesis of oligosaccharides: an overview
Planas, Antoni (Planas Sauter); Faijes, Magda (Afinidad. Vol.59, n.500 (2002), p.295-313, 2002)Retaining glycosidases have been extensively studied for the synthesis of oligosaccharides and glycoconjugates as a convenient enzymatic approach to achieve the required regio- and stereoselectivity in ... -
Novel α-mannose-functionalized poly(β-amino ester) nanoparticles as mRNA vaccines with increased antigen presenting cell selectivity in the spleen
González-Ríos, Nil; Artigues Cladera, Margalida; Guerra Rebollo, Marta; Planas, Antoni (Planas Sauter); Borrós i Gómez, Salvador; Faijes, Magda; Fornaguera Puigvert, Cristina (Journal of Materials Chemistry B, 2023-06-14)mRNA vaccination has emerged as a prominent therapy for the future of medicine. Despite the colossal advance in this technology and worldwide efficacy proof (ca. COVID vaccines), mRNA carriers still ... -
Structural-functional analysis reveals a specific domain organization in family GH20 hexosaminidases
Faijes, Magda; Val Cid, Cristina; Biarnés Fontal, Xevi; Planas, Antoni (Planas Sauter) (PLoS ONE. Vol.10, n.5 (2015), e0128075, 2015-05)Hexosaminidases are involved in important biological processes catalyzing the hydrolysis of N-acetyl-hexosaminyl residues in glycosaminoglycans and glycoconjugates. The GH20 enzymes present diverse ... -
Transglycosylation Activity of Engineered Bifidobacterium Lacto-N-Biosidase Mutants at Donor Subsites for Lacto-N-Tetraose Synthesis
Castejón Vilatersana, Mireia; Faijes, Magda; Planas, Antoni (Planas Sauter) (International Journal of Molecular Sciences, 2021-03-21)The health benefits of human milk oligosaccharides (HMOs) make them attractive targets as supplements for infant formula milks. However, HMO synthesis is still challenging and only two HMOs have been ...