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Green tea extracts containing epigallocatechin-3-gallate modulate facial development in Down syndrome

Starbuck, John M.; Llambrich, Sergi; González, Rubén; Albaigès, Júlia; Sarlé, Anna; Wouters, Jens; González Alzate, Alejandro; Sevillano Domínguez, Xavier; Sharpe, James; Torre, Rafael de la; Dierssen, Mara; Vande Velde, Greetje; Martínez Abadías, Neus (Nature, 2021-02)

Trisomy of human chromosome 21 (Down syndrome, DS) alters development of multiple organ systems, including the face and underlying skeleton. Besides causing stigmata, these facial dysmorphologies can ...