Search
Now showing items 1-10 of 12
Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator
(eLife Sciences Publications, 2017-04)
Light-operated drugs constitute a major target in drug discovery, since they may provide spatiotemporal resolution for the treatment of complex diseases (i.e. chronic pain). JF-NP-26 is an inactive ...
Photosensitive EGFR-Targeted Nanocarriers for Combined Photodynamic and Local Chemotherapy
(MDPI, 2022-02)
The major limitation of any cancer therapy lies in the difficulty of precisely controlling the localization of the drug in the tumor cells. To improve this drawback, our study explores the use of ...
Nanostructured AABB Zn (II) Phthalocyanines as Photodynamic Agents for Bacterial Inactivation
(Wiley, 2023-11)
In this work, the ability of amphiphilic Phthalocyanine (Pc) photosensitizers (PS) (Zn(II)Pcs PS1, PS2, and PS3) to assemble into cationic nanoparticles in water and to photo-inactivate bacterial strains ...
A Double Payload Complex between Hypericin and All-trans Retinoic Acid in the β-Lactoglobulin Protein
(MDPI, 2022)
Combined therapies are usually used to treat acne vulgaris since this approach can tackle various foci simultaneously. Using a combination of spectroscopic, computational, and microbiological techniques ...
Carminic acid linked to silica nanoparticles as pigment/antioxidant bifunctional excipient for pharmaceutical emulsions
(MDPI, 2020-04)
The incorporation of pigments and natural polyphenols into inorganic matrices, resulting in a hybrid material that improves the resistance and chemical stability of the pigments and the antioxidant ...
A near-infrared light-activatable Ru(ii)-coumarin photosensitizer active under hypoxic conditions
(Royal Society of Chemistry, 2023-07-14)
Photodynamic therapy (PDT) represents a promising approach for cancer treatment. However, the oxygen dependency of PDT to generate reactive oxygen species (ROS) hampers its therapeutic efficacy, especially ...
Porficenos para la fotoquimioterapia del cáncer y otras aplicaciones biomédicas
(Asociación de Químicos e Ingenieros del Instituto Químico de Sarrià, 2002)
La terapia fotodinámica (PDT) o fotoquimioterapia del cáncer es una modalidad terapéutica que consiste en la aplicación de compuestos fotosensibilizadores que se acumulan preferentemente en tejidos ...
Bactericidal effect of photodynamic therapy, alone or in combination with mupirocin or linezolid, on Staphylococcus aureus
(Frontiers Media, 2017-05)
Antibiotic treatments frequently fail due to the development of antibiotic resistance, underscoring the need for new treatment strategies. Antimicrobial photodynamic therapy (aPDT) could constitute an ...
Innovative light sources for phototherapy
(De Gruyter, 2022)
The use of light for therapeutic purposes dates back to ancient Egypt, where the sun itself was an innovative source, probably used for the first time to heal skin diseases. Since then, technical ...
Antimicrobial efficacy of solar disinfection in cellulose fiber supported photoactive materials
(Elsevier, 2023-12-29)
According to the World Health Organization, antimicrobial resistance is one of the emerging threats to global health. Therefore, the development of new strategies to mitigate resistant bacterial strains ...