Search
Now showing items 1-10 of 40
Photosensitizing proteins for antibacterial photodynamic inactivation
(Wiley-VCH Verlag, 2020-05)
We review recent applications of water‐soluble proteins as carriers for photosensitizing molecules in antimicrobial photodynamic therapy (aPDT). The low water solubility of photosensitizers and their ...
Development of green/red-absorbing chromophores based on a coumarin scaffold that are useful as caging groups
(American Chemical Society, 2017-05)
We report the design, synthesis, and spectroscopic characterization of a series of push–pull chromophores based on a novel coumarin scaffold in which the carbonyl of the lactone function of the original ...
Synthesis, photophysical characterization and photoinduced antibacterial activity of methylene blue-loaded amino- and mannose-targeted mesoporous silica nanoparticles
(MDPI, 2015-04)
Over the last 20 years, the number of pathogenic multi-resistant microorganisms has grown steadily, which has stimulated the search for new strategies to combat antimicrobial resistance. Antimicrobial ...
Assessing amphiphilic ABAB Zn(II) Phthalocyanines with enhanced photosensitization abilities in In Vitro photodynamic therapy studies against cancer
(MDPI, 2020-01)
We have previously demonstrated that singlet oxygen photosensitization abilities of Zn(II) phthalocyanines (Zn(II)Pcs) are enhanced through α-functionalization with bulky fluorinated substituents (i.e., ...
Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator
(eLife Sciences Publications, 2017-04)
Light-operated drugs constitute a major target in drug discovery, since they may provide spatiotemporal resolution for the treatment of complex diseases (i.e. chronic pain). JF-NP-26 is an inactive ...
Una visión moderna sobre la desactivación de cetonas aromáticas por beta-fenilos
(Asociación de Químicos e Ingenieros del Instituto Químico de Sarrià, 2016-04)
La desactivación por beta fenilos (en inglés, Beta Phenyl Quenching o BPQ) es una reacción que se produce a partir del estado triplete de cetonas aromáticas con un grupo fenilo en posición beta. Esta ...
Photosensitive EGFR-Targeted Nanocarriers for Combined Photodynamic and Local Chemotherapy
(MDPI, 2022-02)
The major limitation of any cancer therapy lies in the difficulty of precisely controlling the localization of the drug in the tumor cells. To improve this drawback, our study explores the use of ...
Nanostructured AABB Zn (II) Phthalocyanines as Photodynamic Agents for Bacterial Inactivation
(Wiley, 2023-11)
In this work, the ability of amphiphilic Phthalocyanine (Pc) photosensitizers (PS) (Zn(II)Pcs PS1, PS2, and PS3) to assemble into cationic nanoparticles in water and to photo-inactivate bacterial strains ...
On the mechanism of Candida tropicalis biofilm reduction by the combined action of naturally-occurring anthraquinones and blue light
(Public Library of Science (PLoS), 2017-07)
The photoprocesses involved in the photo-induced Candida tropicalis biofilm reduction by two natural anthraquinones (AQs), rubiadin (1) and rubiadin-1-methyl ether (2), were examined. Production of ...
Do folate-receptor targeted liposomal photosensitizers enhance photodynamic therapy selectivity?
(Elsevier, 2011-01)
One of the current goals in photodynamic therapy research is to enhance the selective targeting of tumor cells in order to minimize the risk and the extension of unwanted side-effects caused by normal ...