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Short-term exposure to environmental levels of nicotine and cotinine impairs visual motor response in zebrafish larvae through a similar mode of action: Exploring the potential role of zebrafish α7 nAChR
(Elsevier, 2023-12-14)
The current view is that environmental levels of nicotine and cotinine, commonly in the ng/L range, are safe for aquatic organisms. In this study, 7 days post-fertilization zebrafish embryos have been ...
Androgenic activation, impairment of the monoaminergic system and altered behavior in zebrafish larvae exposed to environmental concentrations of fenitrothion
(Elsevier, 2021-06-25)
Fenitrothion is an organophosphorus insecticide usually found in aquatic ecosystems at concentrations in the range of low ng/L. In this manuscript we show that 24 h exposure to environmental concentrations ...
Glyphosate targets fish monoaminergic systems leading to oxidative stress and anxiety
(Elsevier, 2020-11-18)
Glyphosate is the active ingredient of some of the most highly produced and used herbicides worldwide. The intensive applications of glyphosate-based herbicides and its half-life in water lead to its ...
Differential modulation of the central and peripheral monoaminergic neurochemicals by deprenyl in Zebrafish Larvae
(MDPI, 2021-05-23)
Zebrafish embryos and larvae are vertebrate models increasingly used in translational neuroscience research. Behavioral impairment induced by the exposure to neuroactive or neurotoxic compounds is ...
Pharmacological modulation of behaviour, serotonin and dopamine levels in daphnia magna exposed to the monoamine oxidase inhibitor deprenyl
(MDPI, 2021-08-09)
This study assessed the effects of the monoamine oxidase (MAO) inhibitor deprenyl in Daphnia magna locomotor activity. The mechanisms of action of deprenyl were also determined by studying the relationship ...
Phototactic behaviour and neurotransmitter profiles in two Daphnia magna clones: Vertical and horizontal responses to fish kairomones and psychotropic drugs
(Elsevier, 2022-03-18)
Animal behavioural responses are increasingly being used in environmental risk assessment. Nevertheless, behavioural responses are still hampered by a lack of standardisation. Phototactic behaviour in ...
From dysbiosis to neuropathologies: Toxic effects of glyphosate in zebrafish
(Elsevier Inc., 2023-12-26)
Glyphosate, a globally prevalent herbicide known for its selective inhibition of the shikimate pathway in plants, is now implicated in physiological effects on humans and animals, probably due to its ...
Daphnia magna an emerging environmental model of neuro and cardiotoxicity of illicit drugs
(Elsevier, 2024-02-14)
Cocaine, methamphetamine, ectasy (3,4-methylenedioxy amphetamine (MDMA)) and ketamine are among the most consumed drugs worldwide causing cognitive, oxidative stress and cardiovascular problems in humans. ...
Impact of environmentally relevant concentrations of fluoxetine on zebrafish larvae: From gene to behavior
(Elsevier, 2023-12)
Fluoxetine is widely prescribed for the treatment of depressive states, acting at the level of the central nervous system, consequently affecting non-target organisms. This study aimed to investigate ...
Pharmacological modulation of serotonin levels in zebrafish larvae: lessons for identifying environmental neurotoxicants targeting the serotonergic system
(MDPI, 2021-05-25)
This study examines the effects of acute pharmacological modulation of the serotonergic system over zebrafish larvae’s cognitive, basic, and defense locomotor behaviors, using a medium to high throughput ...