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CES1 and SLC6A2 genetic variants as predictors of response to methylphenidate in autism spectrum disorders
(Dove Medical Press, 2022-11)
Purpose
Autistic spectrum disorders (ASD) children and adolescents usually present comorbidities, with 40–70% of them affected by attention deficit hyperactivity disorders (ADHD). The first option of ...
Pharmacogenetic influences on the response to pharmacological treatment in autism spectrum disorders
(OAE Publishing, 2021-07)
Aim: About a third of patients with autism spectrum disorder (ASD) receive pharmacological treatment for comorbid symptoms. However, 30%-50% do not respond adequately and/or present severe and long-lasting ...
Pharmacogenetic interventions improve the clinical outcome of treatment-resistant autistic spectrum disorder sufferers
(MDPI, 2022-05)
BACKGROUND: Autistic spectrum disorders (ASD) are severe neurodevelopmental alterations characterised by deficits in social communication and repetitive and restricted behaviours. About a third of ...
Effects of a multifaceted intervention in psychogeriatric patients: one-year prospective studyEffects of a multifaceted intervention in psychogeriatric patients: one-year prospective study
(BMJ Publishing Group, 2020-06)
Objectives The aetiology of behavioural and psychological symptoms (BPSD) could be related to inadequate treatment in patients with dementia. The aim of this study was to determine how a multifaceted ...