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Pharmacogenetics of antipsychotics: clinical utility and implementationPharmacogenetics of antipsychotics: clinical utility and implementation
(Elsevier, 2020-12)
Decades of research have produced extensive evidence of the contribution of genetic factors to
the efficacy and toxicity of antipsychotics. Numerous genetic variants in genes controlling drug
availability ...
Pharmacogenetic interventions improve the clinical outcome of treatment-resistant autistic spectrum disorder sufferers
(MDPI, 2022-05)
BACKGROUND: Autistic spectrum disorders (ASD) are severe neurodevelopmental alterations characterised by deficits in social communication and repetitive and restricted behaviours. About a third of ...
CES1 and SLC6A2 genetic variants as predictors of response to methylphenidate in autism spectrum disorders
(Dove Medical Press, 2022-11)
Purpose
Autistic spectrum disorders (ASD) children and adolescents usually present comorbidities, with 40–70% of them affected by attention deficit hyperactivity disorders (ADHD). The first option of ...