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Impaired glucose tolerance and cardiovascular risk factors in relation to infertility: a Mendelian randomization analysis in the Norwegian Mother, Father, and Child Cohort Study

Hernáez, Álvaro; Lee, Yunsung; Page, Christian Magnus; Skåra, Karoline Hansen; Håberg, Siri Eldevik; Magnus, Per; Njølstad, Pål R.; Andreassen, Ole A.; Corfield, Elizabeth C.; Havdahl, Alexandra; Fraser, Abigail; Burgess, Stephen; Lawlor, Deborah A.; Magnus, Maria Christine (Oxford University Press, 2023-11)

STUDY QUESTION Are impaired glucose tolerance (as measured by fasting glucose, glycated hemoglobin, and fasting insulin) and cardiovascular disease risk (as measured by low-density lipoprotein cholesterol, ...

Mediterranean diet, energy restriction, physical activity, and atherogenicity of very-low density lipoproteins: findings from two randomized controlled trials

Pérez-Vega, Karla Alejandra; Castañer, Olga; Sanllorente Melenchon, Albert; Lassale, Camille; Ros Rahola, Emilio; Pintó Sala, Xavier; Estruch Riba, Ramon; Salas Salvadó, Jordi; Corella Piquer, Dolores; Alonso Gómez, Ángel M.; Serra Majem, Lluís; Razquin, Cristina; Fiol, Miquel; Lapetra, José; Gómez-Gracia, Enrique; Tinahones Madueño, Francisco J.; Hernáez, Álvaro; Fitó Colomer, Montserrat (Wiley-VCH GmbH, 2023-01)

Scope: Some very-low density lipoprotein (VLDL) properties may render themmore pro-atherogenic. We aimed to assess whether a Mediterranean diet(MedDiet) or an energy-reduced MedDiet with increased ...

Parental infertility and offspring cardiometabolic trajectories: a pooled analysis of three European cohorts

Hernáez, Álvaro; ElHakeem, Ahmed; Barros, Henrique; Vrijkotte, Tanja; Fraser, Abigail; Lawlor, Deborah A.; Magnus, Maria Christine (Elsevier, 2024-05)

Objective To assess whether parental infertility is associated with differences in cardiometabolic trajectories in offspring. Design Pooled observational analysis in three prospective cohorts. Set ...

Risk of cardiovascular disease in women and men with subfertility: the Trøndelag Health Study

Skåra, Karoline Hansen; Asvold, Bjørn O.; Hernáez, Álvaro; Fraser, Abigail; Rich-Edwards, Janet; Farland, Leslie; Næss, Øyvind; Lawlor, Deborah A.; Brumpton, Ben; Magnus, Maria Christine (Elsevier, 2022-07)

Objective: To investigate the association between subfertility and risk of cardiovascular disease (CVD) outcomes. Design: Prospective study. Setting: Population-based cohort. Patient(s): We studied ...

Placental efflux transporters and antiseizure or antidepressant medication use impact birth weight in MoBa cohort

Hernández Hernández, Marta; Cohen, Jacqueline M.; Skåra, Karoline Hansen; Grindstad, Thea; Lee, Yunsung; Magnus, Per; Njølstad, Pål R.; Andreassen, Ole A.; Corfield, Elizabeth C.; Havdahl, Alexandra; Molden, Espen; Furu, Kari; Magnus, Maria Christine; Hernáez, Álvaro (Cell Press, 2024-03)

Low birth weight raises neonatal risks and lifelong health issues and is linked to maternal medication use during pregnancy. We examined data from the Norwegian Mother, Father, and Child Cohort Study ...

Smoking and infertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study

Hernáez, Álvaro; Wootton, Robyn E.; Page, Christian Magnus; Skåra, Karoline Hansen; Fraser, Abigail; Rogne, Tormod; Magnus, Per; Njølstad, Pål R.; Andreassen, Ole A.; Burgess, Stephen; Lawlor, Deborah A.; Magnus, Maria Christine (Elsevier, 2022-07)

Objective To investigate the association between smoking and infertility. Design Prospective study. Setting Nationwide cohort. Patients 28,606 women and 27,096 men with questionnaire and genotype ...

Association of physical activity with high-density lipoprotein functionality in a population-based cohort: the REGICOR study

Viadas, Raúl; Toloba, Andrea; Fernández, Isabel; Sayols Baixeras, Sergi; Hernáez, Álvaro; Schroeder, Helmut; Degano, Irene R.; Lassale, Camille; Marrugat, Jaume; Elosua Llanos, Roberto (Elsevier, 2023-02)

Introduction and objectives To determine the dose-response association between current and past leisure-time physical activity (LTPA), total and at different intensities, and high-density lipoprotein ...

Emotional eating and cognitive restraint mediate the association between sleep quality and BMI in young adults

Zerón-Rugerio, María Fernanda; Hernáez, Álvaro; Cambras, Trinitat; Izquierdo Pulido, María (Elsevier, 2022-03)

This cross-sectional study was designed to investigate whether diet quality and eating behaviors could mediate the association between sleep quality and body mass index (BMI) in young adults. For all ...

Body mass index and subfertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study

Hernáez, Álvaro; Rogne, Tormod; Skåra, Karoline Hansen; Håberg, Siri Eldevik; Page, Christian Magnus; Fraser, Abigail; Burgess, Stephen; Lawlor, Deborah A.; Magnus, Maria Christine (Oxford University Press, 2021-10)

STUDY QUESTION What is the association between BMI and subfertility? SUMMARY ANSWER We observed a J-shaped relationship between BMI and subfertility in both sexes, when using both a standard ...

Cardiovascular disease risk factors and infertility: multivariable analyses and one-sample Mendelian randomization analyses in the Trøndelag Health Study

Skåra, Karoline Hansen; Hernáez, Álvaro; Næss, Øyvind; Fraser, Abigail; Lawlor, Deborah A.; Burgess, Stephen; Brumpton, Ben; Magnus, Maria Christine (Oxford University Press, 2024-05)

STUDY QUESTION Are cardiovascular disease (CVD) risk factors causally associated with higher risk of infertility among women and men? SUMMARY ANSWER We found evidence to support a causal relationship ...