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Interaction between plasma phospholipid odd‑chain fatty acids and GAD65 autoantibodies on the incidence of adult‑onset diabetes: the EPIC‑InterAct case–cohort study

Lampousi, Anna-Maria; Carlsson, Sofia; Edwall Löfvenborg, Josefin; Cabrera-Castro, Natalia; Chirlaque, Maria-Dolores; Fagherazzi, Guy; Franks, Paul W.; Hampe, Christiane; Jakszyn, Paula; Koulman, Albert; Kyrø, Cecilie; Moreno Iribas, Conchi; Nilsson, Peter M.; Panico, Salvatore; Papier, Keren; van der Schouw, Yvonne T.; Schulze, Matthias B.; Weiderpass, Elisabete; Zamora-Ros, Raul; Forouhi, Nita G.; Sharp, Stephen J.; Rolandsson, Olov; Wareham, Nicholas (Springer Nature, 2023-06)

Aims/hypothesis Islet autoimmunity may progress to adult-onset diabetes. We investigated whether circulating odd-chain fatty acids (OCFA) 15:0 and 17:0, which are inversely associated with type 2 ...

Food biodiversity and total and cause-specific mortality in 9 European countries: an analysis of a prospective cohort study

Hanley-Cook, Giles T.; Huybrechts, Inge; Biessy, Carine; Remans, Roseline; Kennedy, Gina; Deschasaux-Tanguy, Mélanie; Murray, Kris A.; Touvier, Mathilde; Skeie, Guri; Kesse-Guyot, Emmanuelle; Argaw, Alemayehu; Casagrande, Corinne; Nicolas, Geneviève; Vineis, Paolo; Millett, Christopher J.; Weiderpass, Elisabete; Ferrari, Pietro; Dahm, Christina C.; Bueno de Mesquita, H. Bas; Sandanger, Torkjel M.; Ibsen, Daniel B.; Freisling, Heinz; Ramne, Stina; Jannasch, Franziska; van der Schouw, Yvonne T.; Schulze, Matthias B.; Tsilidis, Konstantinos K.; Tjønneland, Anne; Ardanaz, Eva; Bodén, Stina; Cirera, Lluís; Gargano, Giuliana; Halkjær, Jytte; Jakszyn, Paula; Johansson, Ingegerd; Katzke, Verena Andrea; Masala, Giovanna; Panico, Salvatore; Rodríguez-Barranco, Miguel; Sacerdote, Carlotta; Srour, Bernard; Tumino, Rosario; Riboli, Elio; Gunter, Marc J.; Jones, Andrew D.; Lachat, Carl (Public Library of Science (PLoS), 2021-10-18)

Background Food biodiversity, encompassing the variety of plants, animals, and other organisms consumed as food and drink, has intrinsic potential to underpin diverse, nutritious diets and improve Earth ...

Nutritional assessment of plant-based meat alternatives: a comparison of nutritional information of plant-based meat alternatives in Spanish supermarkets

Rizzolo-Brime, Lucía; Puyol Martin, Yael; Jakszyn, Paula; Orta-Ramirez, Alicia (MDPI, 2023-03)

Since the classification of processed meat as carcinogenic by the International Agency for Research on Cancer (IARC) in 2015, an increase in consumption of plant-based meat alternatives (PBMAs) has ...

Characterization of the degree of food processing in the European Prospective Investigation into Cancer and Nutrition: application of the Nova classification and validation using selected biomarkers of food processing

Huybrechts, Inge; Rauber, Fernanda; Nicolas, Geneviève; Casagrande, Corinne; Kliemann, Nathalie; Wedekind, Roland; Biessy, Carine; Scalbert, Augustin; Touvier, Mathilde; Aleksandrova, Krasimira; Jakszyn, Paula; Skeie, Guri; Bajracharya, Rashmita; Boer, Jolanda M.A.; Borné, Yan; Chajes, Veronique; Dahm, Christina C.; Dansero, Lucia; Guevara, Marcela; Heath, Alicia K.; Ibsen, Daniel B.; Papier, Keren; Katzke, Verena Andrea; Kyrø, Cecilie; Masala, Giovanna; Molina-Montes, Esther; Robinson, Oliver J.K.; Santiuste de Pablos, Carmen; Schulze, Matthias B.; Simeon, Vittorio; Sonestedt, Emily; Tjønneland, Anne; Tumino, Rosario; van der Schouw, Yvonne T.; Verschuren, Monique; Vozar, Beatrice; Winkvist, Anna; Gunter, Marc J.; Monteiro, Carlos A.; Millett, Christopher J.; Bertazzi Levy, Renata (Frontiers, 2022-12)

Background: Epidemiological studies have demonstrated an association between the degree of food processing in our diet and the risk of various chronic diseases. Much of this evidence is based on the ...

Association between pre-diagnostic circulating lipid metabolites and colorectal cancer risk: a nested case–control study in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Harewood, Rhea; Rothwell, Joseph A.; Bešević, Jelena; Viallon, Vivian; Achaintre, David; Gicquiau, Audrey; Rinaldi, Sabina; Wedekind, Roland; Prehn, Cornelia; Adamski, Jerzy; Schmidt, Julie A.; Jacobs, Inarie; Tjønneland, Anne; Olsen, Anja; Severi, Gianluca; Kaaks, Rudolf; Katzke, Verena Andrea; Schulze, Matthias B.; Prada, Marcela; Masala, Giovanna; Agnoli, Claudia; Panico, Salvatore; Sacerdote, Carlotta; Jakszyn, Paula; Sánchez, María-José; Castilla, Jesús; Chirlaque, Maria-Dolores; Aizpurua Atxega, Amaia; Van Guelpen, Bethany; Heath, Alicia K.; Papier, Keren; Tong, Tammy Y. N.; Summers, Scott A.; Playdon, Mary; Cross, Amanda J.; Keski-Rahkonen, Pekka; Chajès, Véronique; Murphy, Neil; Gunter, Marc J. (Elsevier, 2024-03)

Background Altered lipid metabolism is a hallmark of cancer development. However, the role of specific lipid metabolites in colorectal cancer development is uncertain. Methods In a case–control study ...

Factors associated with serum ferritin levels and iron excess: results from the EPIC‑EurGast study

Iglesias Vázquez, Lucía; Arija, Victoria; Aranda, Núria; Aglago, Elom K; Cross, Amanda J.; Schulze, Matthias B.; Quintana Pacheco, Daniel; Kühn, Tilman; Weiderpass, Elisabete; Tumino, Rosario; Redondo‑Sánchez, Daniel; Santucci de Magistris, Maria; Palli, Domenico; Ardanaz, Eva; Laouali, Nasser; Sonestedt, Emily; Drake, Isabel; Rizzolo-Brime, Lucía; Santiuste, Carmen; Sacerdote, Carlotta; Quirós, José Ramón; Amiano, Pilar; Agudo, Antonio; Jakszyn, Paula (Springer Nature, 2021-07)

Purpose Excess iron is involved in the development of non-communicable diseases such as cancer, type 2 diabetes and cardiovascular conditions. We aimed to describe the prevalence of excess iron and its ...

Sex- and site-specific associations of circulating lipocalin 2 and incident colorectal cancer: Results from the EPIC cohort

Reichmann, Robin; Nimptsch, Katharina; Pischon, Tobias; Gunter, Marc J.; Jenab, Mazda; Eriksen, Anne Kirstine; Tjonneland, Anne; Janke, Jürgen; Katzke, Verena Andrea; Kaaks, Rudolf; Schulze, Matthias B.; Eichelmann, Fabian; Masala, Giovanna; Sieri, Sabina; Pasanisi, Fabrizio; Tumino, Rosario; Giraudo, Maria Teresa; Rothwell, Joseph A.; Severi, Gianluca; Jakszyn, Paula; Sanchez-Perez, Maria Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Guevara, Marcela; Van Guelpen, Bethany; Aglago, Elom K; Heath, Alicia K.; Smith-Byrne, Karl; Weiderpass, Elisabete; Aleksandrova, Krasimira (Wiley Online Library, 2024-11)

Experimental research has uncovered lipocalin 2 (LCN2) as a novel biomarker implicated in the modulation of intestinal inflammation, metabolic homeostasis, and colon carcinogenesis. However, evidence ...

Breakfast size and prevalence of metabolic syndrome in the European Prospective Investigation into Cancer and Nutrition (EPIC) spanish cohort

Lujan-Barroso, Leila; Iglesias, Lucia; Zamora-Ros, Raul; Lasheras-Mayo, Maria Cristina; Sánchez, María-José; Cabrera-Castro, Natalia; Delfrad, Josu; Amiano, Pilar; Molina-Montes, Esther; Colorado-Yohar, Sandra; Moreno Iribas, Conchi; Dorronsoro, Ane; Rodríguez-Barranco, Miguel; Chirlaque, Maria-Dolores; Aizpurua, Amaia; Agudo, Antonio; Quirós, José Ramón; Jakszyn, Paula (MDPI, 2023-01)

Background: Recent evidence suggest that energy distribution during the daytimecould be a potential determinant for the development of metabolic syndrome (MetS). Objective: To cross-sectionally assess ...

Multimorbidity in acute ischemic stroke and its impact on short-term mortality: A Chilean nationwide database analysis

Gonzalez McCawley, Francisca; Allende Echanez, Maria Ignacia; Núñez, Marilaura; Delgado, Iris; Jakszyn, Paula; Delfino, Carlos; Anderson, Craig S.; Munoz Venturelli, Paula (Elsevier, 2025-02)

Background Multimorbidity predicts a worse prognosis for various diseases but its impact in people after an acute ischemic stroke (AIS) in developing societies is not well established. We aimed to ...

Inflammatory potential of the diet and risk of breast cancer in the European Investigation into Cancer and Nutrition (EPIC) study

Castro Espin, Carlota; Agudo, Antonio; Bonet, Catalina; Katzke, Verena Andrea; Turzanski‑Fortner, Renée; Aleksandrova, Krasimira; Schulze, Matthias B.; Tjønneland, Anne; Dahm, Christina C.; Quirós, José Ramón; Sánchez, María-José; Amiano, Pilar; Chirlaque, Maria-Dolores; Ardanaz, Eva; Masala, Giovanna; Sieri, Sabina; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; May, Anne-Marie; Bodén, Stina; Gram, Inger Torhild; Skeie, Guri; Laouali, Nasser; Shah, Sanam; Severi, Gianluca; Aune, Dagfnn; Merritt, Melissa; Cairat, Manon; Weiderpass, Elisabete; Riboli, Elio; Dossus, Laure; Jakszyn, Paula (Springer Nature, 2021-06)

The role of chronic infammation on breast cancer (BC) risk remains unclear beyond as an underlying mechanism of obesity and physical activity. We aimed to evaluate the association between the infammatory ...