Now showing items 1-20 of 27

    • A lifestyle intervention with an energy-restricted Mediterranean diet and physical activity enhances HDL function: a substudy of the PREDIMED-Plus randomized controlled trial 

      Sanllorente Melenchon, Albert; Soria Florido, María Trinidad; Castañer, Olga; Lassale, Camille; Salas Salvadó, Jordi; Martínez-González, Miguel Ángel; Subirana, Isaac; Ros Rahola, Emilio; Corella Piquer, Dolores; Estruch Riba, Ramon; Tinahones Madueño, Francisco J.; Hernáez, Álvaro; Fitó Colomer, Montserrat (The American Journal of Clinical Nutrition, 2021, 114(5): 1666-1674, 2021-11)
      Background Consumption of a Mediterranean diet, adequate levels of physical activity, and energy-restricted lifestyle interventions have been individually associated with improvements in HDL functions. ...
    • Association between lifestyle and hypertriglyceridemic waist phenotype in the PREDIMED-Plus Study 

      Fernández-García, José Carlos; Muñoz-Garach, Araceli; Martínez-González, Miguel Ángel, 1957-; Salas Salvadó, Jordi; Corella Piquer, Dolores; Hernáez, Álvaro; Romaguera, Dora; Vioque, Jesús; Alonso Gómez, Ángel M.; Wärnberg, Julia; Martínez, José Alfredo; Serra Majem, Lluís; Estruch Riba, Ramon; Lapetra, José; Pintó Sala, Xavier; Tur, Josep A.; Garcia-Rios, Antonio; García-Molina, Laura; Gaforio, Jose J; Matía Martín, Pilar; Daimiel, Lidia; Martín Sánchez, Vicente; Vidal, Josep; Prieto, Lucia; Ros Rahola, Emilio; Goñi, Nuria; Babio, Nancy; Ortega-Azorin, Carolina; Castañer, Olga; Konieczna, Jadwiga; Notario Barandiaran, Leyre; Vaquero Luna, Jessica; Benavente Marín, Juan Carlos; Zulet, M. Angeles; Sanchez Villegas, Almudena; Sacanella Meseguer, Emilio; Gómez Huelgas, Ricardo; Miró-Moriano, Leticia; Gimenez-Gracia, Mariano; Julibert, Alicia; Razquin, Cristina; Basora, Josep; Portolés, Olga; Goday, Alberto; Galmés-Panadés, Aina M.; López-García, Carmen M.; Moreno-Rodriguez, Anai; Toledo, Estefanía; Díaz López, Andrés; Fitó Colomer, Montserrat; Tinahones Madueño, Francisco J.; Bernal-López, M. Rosa (Obesity, 2020, 28(3): 537-543, 2020-02)
      Objective The hypertriglyceridemic waist (HTGW) phenotype is characterized by abdominal obesity and high levels of triglycerides. In a cross-sectional assessment of PREDIMED-Plus trial participants at ...
    • Association of physical activity with high-density lipoprotein functionality in a population-based cohort: the REGICOR study 

      Viadas, Raúl; Toloba, Andrea; Fernández, Isabel; Sayols Baixeras, Sergi; Hernáez, Álvaro; Schroeder, Helmut; Degano, Irene R.; Lassale, Camille; Marrugat, Jaume; Elosua Llanos, Roberto (Revista española de cardiología, 2023, 76(2): 86-93, 2023-02)
      Introduction and objectives To determine the dose-response association between current and past leisure-time physical activity (LTPA), total and at different intensities, and high-density lipoprotein ...
    • Association of pre-pandemic high-density lipoprotein cholesterol with risk of COVID-19 hospitalisation and death: The UK Biobank cohort study 

      Lassale, Camille; Hamer, Mark; Hernáez, Álvaro; Gale, Catharine R.; Batty, G. David (Preventive Medicine Reports, 2021, 23: 101461, 2021-06)
      There is growing evidence of, and biological plausibility for, elevated levels of high-density lipoprotein cholesterol (HDL-C) being related to lower rates of respiratory disease. We tested whether ...
    • Blood DNA methylation signature of diet quality and association with cardiometabolic traits 

      Domínguez-Barragán, Jorge; Fernández Sanlés, Alba; Hernáez, Álvaro; Llauradó-Pont, Joana; Marrugat, Jaume; Robinson, Oliver; Tzoulaki, Ioanna; Elosua Llanos, Roberto; Lassale, Camille (European Journal of Preventive Cardiology, 2024, 31, 191-202, 2023-10)
      Aims Diet quality might influence cardiometabolic health through epigenetic changes, but this has been little investigated in adults. Our aims were to identify cytosine–phosphate–guanine (CpG) dinucleotides ...
    • Body mass index and subfertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study 

      Hernáez, Álvaro; Rogne, Tormod; Skåra, Karoline Hansen; Håberg, Siri Eldevik; Page, Christian Magnus; Fraser, Abigail; Burgess, Stephen; Lawlor, Deborah A.; Magnus, Maria Christine (Human Reproduction, 2021, 36(12), 3141-3151, 2021-10)
      STUDY QUESTION What is the association between BMI and subfertility? SUMMARY ANSWER We observed a J-shaped relationship between BMI and subfertility in both sexes, when using both a standard ...
    • Breakfast energy intake and dietary quality and trajectories of cardiometabolic risk factors in older adults 

      Pérez-Vega, Karla Alejandra; Lassale, Camille; Zomeño, Dolors; Castañer, Olga; Salas Salvadó, Jordi; Basterra-Gortari, Francisco Javier; Corella Piquer, Dolores; Estruch Riba, Ramon; Ros Rahola, Emilio; Tinahones Madueño, Francisco J.; Blanchart, Gemma; Malcampo, Mireia; Muñoz Aguayo, Daniel; Schröder, Helmut; Fitó Colomer, Montserrat; Hernáez, Álvaro (The Journal of nutrition, health and aging, 2024, 28(12): 100406, 2024-12)
      Objectives Not skipping breakfast is associated with a better overall diet quality and lower cardiometabolic risk. However, the impact of calorie intake and dietary quality of breakfast on cardiovascular ...
    • Cancer signaling transcriptome is upregulated in type 2 diabetes mellitus 

      Almanza Aguilera, Enrique; Hernáez, Álvaro; Corella Piquer, Dolores; Sanllorente Melenchon, Albert; Ros Rahola, Emilio; Portolés, Olga; Valussi, Julieta; Estruch Riba, Ramon; Coltell, Oscar; Subirana, Isaac; Canudas i Puig, Sílvia; Razquin, Cristina; Blanchart, Gemma; Nonell, Lara; Fitó Colomer, Montserrat; Castañer, Olga (Journal of clinical medicine, 2020, vol. 10, núm. 1, 85, 2020-12-29)
      We aimed to explore the differences in the whole transcriptome of peripheral blood mononuclear cells between elderly individuals with and without type 2 diabetes (T2D). We conducted a microarray-based ...
    • Cardiovascular disease risk factors and infertility: multivariable analyses and one-sample Mendelian randomization analyses in the Trøndelag Health Study 

      Skåra, Karoline Hansen; Hernáez, Álvaro; Næss, Øyvind; Fraser, Abigail; Lawlor, Deborah A.; Burgess, Stephen; Brumpton, Ben; Magnus, Maria Christine (Human Reproduction Open, 2024, 2024 (3), hoae033, 2024-05)
      STUDY QUESTION Are cardiovascular disease (CVD) risk factors causally associated with higher risk of infertility among women and men? SUMMARY ANSWER We found evidence to support a causal relationship ...
    • Emotional eating and cognitive restraint mediate the association between sleep quality and BMI in young adults 

      Zerón-Rugerio, María Fernanda; Hernáez, Álvaro; Cambras, Trinitat; Izquierdo Pulido, María (Appetite, 2022, 170: 105899, 2022-03)
      This cross-sectional study was designed to investigate whether diet quality and eating behaviors could mediate the association between sleep quality and body mass index (BMI) in young adults. For all ...
    • Exceso de peso en España: situación actual, proyecciones para 2030 y sobrecoste directo estimado para el Sistema Nacional de Salud 

      Hernáez, Álvaro; Zomeño, Dolors; Degano, Irene R.; Pérez Fernández, Sílvia; Goday, Alberto; Vila, Joan; Civeira, Fernando; Moure, Ricardo; Marrugat, Jaume (Revista española de cardiología, 2019, 72(11): 916-924, 2019-11)
      Introducción y objetivos El exceso de peso potencia algunas enfermedades crónicas y reduce la calidad de vida, y su prevalencia crece en todo el mundo. El objetivo es estimar la evolución del exceso ...
    • Fruit and vegetable consumption is inversely associated with plasma saturated fatty acids at baseline in Predimed Plus Trial 

      Domínguez-López, Inés; Marhuenda-Muñoz, María; Tresserra-Rimbau, Anna; Hernáez, Álvaro; Moreno, Juan José; Martínez-González, Miguel Ángel; Salas Salvadó, Jordi; Corella Piquer, Dolores; Fitó Colomer, Montserrat; Martínez, José Alfredo; Alonso Gómez, Ángel M.; Wärnberg, Julia; Vioque, Jesús; Romaguera, Dora; López Miranda, José; Bernal-López, M. Rosa; Lapetra, José; Serra Majem, Lluís; Bueno-Cavanillas, Aurora; Tur, Josep A.; Martín Sánchez, Vicente; Pintó Sala, Xavier; Delgado-Rodríguez, Miguel; Matía Martín, Pilar; Vidal, Josep; Vázquez, Clotilde; Daimiel, Lidia; Serra-Mir, Mercè; Vázquez Ruiz, Zenaida; Nishi, Stephanie K.; Sorli, Jose V.; Castañer, Olga; Abete, Itziar; Vaquero Luna, Jessica; Carabaño-Moral, Rosa; Asencio, Alberto; Prohens, Lara; Garcia-Rios, Antonio; Casas, Rosa; Gómez-Pérez, Ana Maria; Santos Lozano, José Manuel; Razquin, Cristina; Martínez, María Ángeles; Saiz, Carmen; Robledo-Pastor, Vanesa; Zulet, M. Angeles; Salaverria, Itziar; Eguaras, Sonia; Babio, Nancy; Malcampo, Mireia; Ros, Emilio; Estruch Riba, Ramon; López-Sabater, Maria Carmen; Lamuela Raventós, Rosa Ma. (Molecular Nutrition and Food Research, 2021, 65(17): 2100363, 2021-09)
      Scope Plasma fatty acids (FAs) are associated with the development of cardiovascular diseases and metabolic syndrome. The aim of our study is to assess the relationship between fruit and vegetable (F&V) ...
    • High-density lipoprotein characteristics and coronary artery disease: a Mendelian randomization study 

      Prats Uribe, Albert; Sayols Baixeras, Sergi; Fernández Sanlés, Alba; Subirana, Isaac; Carreras-Torres, Robert; Vilahur, Gemma; Civeira, Fernando; Marrugat, Jaume; Fitó Colomer, Montserrat; Hernáez, Álvaro; Elosua Llanos, Roberto (Metabolism Clinical and Experimental, 2020, 112: 154351, 2020-09)
      Background To assess whether genetically determined quantitative and qualitative HDL characteristics were independently associated with coronary artery disease (CAD). Methods We designed a two-sample ...
    • Impaired glucose tolerance and cardiovascular risk factors in relation to infertility: a Mendelian randomization analysis in the Norwegian Mother, Father, and Child Cohort Study 

      Hernáez, Álvaro; Lee, Yunsung; Page, Christian Magnus; Skåra, Karoline Hansen; Håberg, Siri Eldevik; Magnus, Per; Njølstad, Pål R.; Andreassen, Ole A.; Corfield, Elizabeth C.; Havdahl, Alexandra; Fraser, Abigail; Burgess, Stephen; Lawlor, Deborah A.; Magnus, Maria Christine (Human Reproduction, 2024, 39(2), 436-441, 2023-11)
      STUDY QUESTION Are impaired glucose tolerance (as measured by fasting glucose, glycated hemoglobin, and fasting insulin) and cardiovascular disease risk (as measured by low-density lipoprotein cholesterol, ...
    • Increased consumption of virgin olive oil, nuts, legumes, whole grains, and fish promotes HDL functions in humans 

      Hernáez, Álvaro; Sanllorente Melenchon, Albert; Castañer, Olga; Martínez-González, Miguel Ángel, 1957-; Ros Rahola, Emilio; Pintó Sala, Xavier; Estruch Riba, Ramon; Salas Salvadó, Jordi; Corella Piquer, Dolores; Alonso Gómez, Ángel M.; Serra Majem, Lluís; Fiol, Miquel; Lapetra, José; Gómez-Gracia, Enrique; de la Torre, Rafael; Lamuela Raventós, Rosa Ma.; Fitó Colomer, Montserrat (Molecular nutrition and food research, 2019, 63(6): 1800847, 2019-01)
      Scope To evaluate whether increases in the consumption of cardioprotective food groups (virgin olive oil, nuts, fruits/vegetables, legumes, whole grains, fish, and wine) are associated with improvements ...
    • Mediterranean diet and antihypertensive drug use: a randomized controlled trial 

      Ribó-Coll, Margarita; Lassale, Camille; Sacanella Meseguer, Emilio; Ros Rahola, Emilio; Toledo, Estefanía; Sorlí, José V.; Babio, Nancy; Lapetra, José; Gómez-Gracia, Enrique; Alonso Gómez, Ángel M.; Fiol, Miquel; Serra Majem, Lluís; Pintó Sala, Xavier; Castañer, Olga; Díez Espino, Javier; González, José I.; Becerra-Tomás, Nerea; Cofán Pujol, Montserrat; Díaz López, Andrés; Estruch Riba, Ramon; Hernáez, Álvaro (Journal of hypertension, 2021, 39(6): 1230-1237, 2021-06)
      Objective: To examine in older individuals at high cardiovascular risk whether following a Mediterranean diet decreased the necessity of antihypertensive drugs and modulated their associated cardiovascular ...
    • Mediterranean diet and white blood cell count — A randomized controlled trial 

      Hernáez, Álvaro; Lassale, Camille; Castro-Barquero, Sara; Babio, Nancy; Ros Rahola, Emilio; Castañer, Olga; Tresserra-Rimbau, Anna; Pintó Sala, Xavier; Martínez-González, Miguel Ángel; Corella Piquer, Dolores; Salas Salvadó, Jordi; Alonso Gómez, Ángel M.; Lapetra, José; Fiol, Miquel; Gómez-Gracia, Enrique; Serra Majem, Lluís; Sacanella Meseguer, Emilio; García-Arellano, Ana; Sorlí, José V.; Díaz López, Andrés; Cofán Pujol, Montserrat; Estruch Riba, Ramon (Foods, 2021, 10(6): 1268, 2021-06)
      We aimed to assess the effects of the antioxidant-rich Mediterranean diet (MedDiet) on white blood cell count. Our study population included participants in the PREvención con DIeta MEDiterránea study ...
    • Mediterranean diet decreases the initiation of use of vitamin K epoxide reductase inhibitors and their associated cardiovascular risk: a randomized controlled trial 

      Castro-Barquero, Sara; Ribó-Coll, Margarita; Lassale, Camille; Tresserra-Rimbau, Anna; Castañer, Olga; Pintó Sala, Xavier; Martínez-González, Miguel Ángel, 1957-; Sorlí, José V.; Salas Salvadó, Jordi; Lapetra, José; Gómez-Gracia, Enrique; Alonso Gómez, Ángel M.; Fiol Sala, Miguel; Serra Majem, Lluís; Sacanella Meseguer, Emilio; Basterra-Gortari, Francisco Javier; Portolés, Olga; Babio, Nancy; Cofán Pujol, Montserrat; Ros Rahola, Emilio; Estruch Riba, Ramon; Hernáez, Álvaro (Nutrients, 2020, no. 12: 3895, 2020-12-19)
      Our aim is to assess whether following a Mediterranean Diet (MedDiet) decreases the risk of initiating antithrombotic therapies and the cardiovascular risk associated with its use in older individuals ...
    • Mediterranean diet maintained platelet count within a healthy range and decreased thrombocytopenia-related mortality risk: a randomized controlled trial 

      Hernáez, Álvaro; Lassale, Camille; Castro-Barquero, Sara; Ros Rahola, Emilio; Tresserra i Rimbau, Anna; Castañer, Olga; Pintó Sala, Xavier; Vázquez Ruiz, Zenaida; Sorlí, José V.; Salas Salvadó, Jordi; Lapetra, José; Gómez-Gracia, Enrique; Alonso Gómez, Ángel M.; Fiol, Miquel; Serra Majem, Lluís; Sacanella Meseguer, Emilio; Razquin, Cristina; Corella Piquer, Dolores; Guasch-Ferré, Marta; Cofán Pujol, Montserrat; Estruch Riba, Ramon (Nutrients, 2021, 13, 559, 2021-02)
      There is little information on the dietary modulation of thrombosis-related risk factors such as platelet count. We aimed to assess the effects of Mediterranean diet (MedDiet) on platelet count and ...
    • Mediterranean diet, energy restriction, physical activity, and atherogenicity of very-low density lipoproteins: findings from two randomized controlled trials 

      Pérez-Vega, Karla Alejandra; Castañer, Olga; Sanllorente Melenchon, Albert; Lassale, Camille; Ros Rahola, Emilio; Pintó Sala, Xavier; Estruch Riba, Ramon; Salas Salvadó, Jordi; Corella Piquer, Dolores; Alonso Gómez, Ángel M.; Serra Majem, Lluís; Razquin, Cristina; Fiol, Miquel; Lapetra, José; Gómez-Gracia, Enrique; Tinahones Madueño, Francisco J.; Hernáez, Álvaro; Fitó Colomer, Montserrat (Molecular Nutrition and Food Research, 2023, 67(1): 2200338, 2023-01)
      Scope: Some very-low density lipoprotein (VLDL) properties may render themmore pro-atherogenic. We aimed to assess whether a Mediterranean diet(MedDiet) or an energy-reduced MedDiet with increased ...