Now showing items 1-3 of 3

    • A simplified implementation of the stationary liquid mass balance method for on‐line OUR monitoring in animal cell cultures 

      Lecina i Veciana, Martí; Fontova i Sosa, Andreu Francesc; López Repullo, Jonatan; Martínez-Monge, Iván; Comas Sánchez, Pere; Bragós Bardia, Ramon; Cairó, Jordi Joan (Journal of Chemical Technology and Biotechnology. Vol.93, n.6 (2018), p.1757-1766, 2018-05)
      BACKGROUND Compared with other methods, the stationary liquid mass balance method for oxygen uptake rate (OUR) determination offers advantages in terms of estimation accuracy and reduction of stress. ...
    • Monitoring Tools for the Development of High Cell Density Culture Strategies 

      Lecina i Veciana, Martí; Comas Sánchez, Pere; Martínez-Monge, Iván; Cairó, Jordi Joan (Cell Culture Engineering and Technology. Cell Engineering, 2022-02-20)
      Biopharmaceuticals market has been constantly increasing during the last years, what is transforming the manufacturing industry of biomolecules. The efforts have been put into better understanding how ...
    • The Effect of the Expression of the Antiapoptotic BHRF1 Gene on the Metabolic Behavior of a Hybridoma Cell Line 

      Martínez-Monge, Iván; Comas Sánchez, Pere; Catalán-Tatjer, David; Prat, Jordi; Casablancas, Antoni; Paredes, Carlos J.; Lecina i Veciana, Martí; Cairó, Jordi Joan (Applied Sciences, 2021-07-06)
      One of the most important limitations of mammalian cells-based bioprocesses, and particularly hybridoma cell lines, is the accelerated metabolism related to glucose and glutamine consumption. The high ...