Browsing by Author "Guix Rafols, Francesc Xavier"

Now showing items 1-3 of 3

    • Bioelectric stimulation outperforms brain derived neurotrophic factor in promoting neuronal maturation 

      Diego Santiago , María del Pilar ; González, María Ujué; Zamora Sánchez, Esther María; Cortés Carrillo, Núria; Dotti, Carlos ; Guix Rafols, Francesc Xavier; Mobini, Sahba (Scientific Reports 2025, 15, 2025-02)
      Neuronal differentiation and maturation are crucial for developing research models and therapeutic applications. Brain-derived neurotrophic factor (BDNF) is a widely used biochemical stimulus for promoting ...

    • Cognitive decline in diabetic mice predisposed to Alzheimer’s disease is greater than in wild type 

      Carus Cadavieco, Marta; Berenguer López, Inés; Montoro Canelo, Alba; Serrano Lope, Miguel A; González de la Fuente, Sandra; Aguado, Begoña; Fernández Rodrigo, Alba; Saido, Takaomi C; Frank García, Ana; Venero, César; Esteban, José A; Guix Rafols, Francesc Xavier; Dotti, Carlos G (Life Science Alliance 2023, 6 (6), e202201789, 2023-06)
      In this work, we tested the hypothesis that the development of dementia in individuals with type 2 diabetes (T2DM) requires a genetic background of predisposition to neurodegenerative disease. As a proof ...

    • Loss of Cldn5 -and increase in Irf7-in the hippocampus and cerebral cortex of diabetic mice at the early symptomatic stage 

      Carús-Cadavieco, Marta; González de la Fuente, Sandra; Berenguer López, Inés; Serrano Lope, Miguel Ángel; Aguado, Begoña; Guix Rafols, Francesc Xavier; Palomer, Ernest; Dotti, Carlos (Nutrition and Diabetes. 2024;14:64, 2024-08-15)
      Analyzing changes in gene expression within specific brain regions of individuals with Type 2 Diabetes (T2DM) who do not exhibit significant cognitive deficits can yield valuable insights into the ...