Now showing items 1-4 of 4

    • A near-infrared light-activatable Ru(ii)-coumarin photosensitizer active under hypoxic conditions 

      Ortega Forte, Enrique; Rovira, Anna; López Corrales, Marta; Hernández García, Alba; Ballester, Francisco José; Izquierdo García, Eduardo; Jordà Redondo, Mireia; Bosch, Manel; Nonell, Santi; Santana, María Dolores; Ruiz, José; Marchán, Vicente; Gasser, Gilles (Chemical Space 2023, 15(26), 2023-07-14)
      Photodynamic therapy (PDT) represents a promising approach for cancer treatment. However, the oxygen dependency of PDT to generate reactive oxygen species (ROS) hampers its therapeutic efficacy, especially ...
    • Antimicrobial efficacy of solar disinfection in cellulose fiber supported photoactive materials 

      Langerreiter, Daniel; Solin, Katariina; Jordà Redondo, Mireia; Bresolí Obach, Roger; Fliri, Lukas; Nonell, Santi; Kostiainen, Mauri A.; Anaya-Plaza, Eduardo (Materials Today Communications. 2024;38:107858, 2023-12-29)
      According to the World Health Organization, antimicrobial resistance is one of the emerging threats to global health. Therefore, the development of new strategies to mitigate resistant bacterial strains ...
    • Exploring Structure–Activity Relationships in Photodynamic Therapy Anticancer Agents Based on Ir(III)-COUPY Conjugates 

      Rovira, Anna; Ortega Forte, Enrique; Hally, Cormac; Jordà Redondo, Mireia; Abad-Montero, Diego; Vigueras, Gloria; Martínez, Jesús I.; Bosch, Manel; Nonell, Santi; Ruiz, José; Marchán, Vicente (Journal of Medicinal Chemistry 2023, 66 (12), 2023-06-22)
      Photodynamic therapy holds great promise as a non-invasive anticancer tool against drug-resistant cancers. However, highly effective, non-toxic, and reliable photosensitizers with operability under ...
    • Nanostructured AABB Zn (II) Phthalocyanines as Photodynamic Agents for Bacterial Inactivation 

      Paramio, Irene; Salazar, Ainhoa; Jordà Redondo, Mireia; Nonell, Santi; Torres, Tomás; De la Torre, Gema (Advanced Therapeutics 2023, 6 (11), 2300116, 2023-11)
      In this work, the ability of amphiphilic Phthalocyanine (Pc) photosensitizers (PS) (Zn(II)Pcs PS1, PS2, and PS3) to assemble into cationic nanoparticles in water and to photo-inactivate bacterial strains ...