Browsing by Author "Navalón López, María"
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Liver-targeted nanoparticles delivering nitric oxide reduce portal hypertension in cirrhotic rats
Perramón Corominas, Meritxell; Navalón López, María; Fernández Varo, Guillermo; Moreno Lanceta, Alazne; García Jiménez, Rocío; Faneca Farrés, Joana; López-Moya, Mario; Fornaguera Puigvert, Cristina; García-Villoria, Judith; Morales-Ruiz, Manuel; Melgar Lesmes, Pedro; Borrós i Gómez, Salvador; Jiménez, Wladimiro (2024-01-13)Nitric oxide (NO) is a small vasodilator playing a key role in the pathogenesis of portal hypertension. Here, we assessed the potential therapeutic effect of a NO donor targeted to the liver by ... -
PExM: polyplex expansion microscopy for cell trafficking studies
Navalón López, María; Castells Colldeforns, Pau; Pujals, Sílvia; Fornaguera Puigvert, Cristina; Borrós i Gómez, Salvador (Nanoscale. 2024;16:11969-11976, 2024-06-03)Nanomedicine is a field at the intersection of nanotechnology and medicine, promising due to its potential to revolutionize healthcare. Despite its long trajectory, there is still a long road ahead for ... -
Unravelling the role of individual components in pBAE/polynucleotide polyplexes in the synthesis of tailored carriers for specific applications: on the road to rational formulations
Navalón López, María; Dols-Perez, Aurora; Grijalvo, Santiago; Fornaguera Puigvert, Cristina; Borrós i Gómez, Salvador (Nanoscale Advances 2023, 7 (6), 2023-03)Oligopeptide end–modified poly(β-amino ester)s (OM-pBAEs) offer a means for the effective implementation of gene therapeutics in the near future. A fine-tuning of OM-pBAEs to meet application requirements ...