Browsing by Author "Viappiani, Cristiano"
Now showing items 1-7 of 7
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A Double Payload Complex between Hypericin and All-trans Retinoic Acid in the β-Lactoglobulin Protein
Rodríguez Amigo, Beatriz; Hally, Cormac; Roig Yanovsky, Núria; Delcanale, Pietro; Abbruzzetti, Stefania; Agut Bonsfills, Montserrat; Viappiani, Cristiano; Nonell, Santi (Antibiotics, 11(2), 2022, 282, 2022)Combined therapies are usually used to treat acne vulgaris since this approach can tackle various foci simultaneously. Using a combination of spectroscopic, computational, and microbiological techniques ... -
Concanavalin A Delivers a Photoactive Protein to the Bacterial Wall
Mussini, Andrea; Delcanale, Pietro; Berni, Melissa; Pongolini, Stefano; Agut Bonsfills, Montserrat; Steinbach, Peter J.; Nonell, Santi; Abbruzzetti, Stefania; Viappiani, Cristiano (International Journal of Molecular Sciences. 2024;25(11):5751, 2024-05-25)Modular supramolecular complexes, where different proteins are assembled to gather targeting capability and photofunctional properties within the same structures, are of special interest for bacterial ... -
Photosensitizing proteins for antibacterial photodynamic inactivation
Nonell, Santi; Hally, Cormac; Delcanale, Pietro; Viappiani, Cristiano; Abbruzzetti, Stefania (Translational Biophotonics. Vol.2, n.1-2 (2020) e201900031, 2020-05)We review recent applications of water‐soluble proteins as carriers for photosensitizing molecules in antimicrobial photodynamic therapy (aPDT). The low water solubility of photosensitizers and their ... -
Subdiffraction localization of a nanostructured photosensitizer in bacterial cells
Agut Bonsfills, Montserrat; Nonell, Santi; Delcanale, Pietro; Pennacchietti, Francesca; Maestrini, Giulio; Rodríguez Amigo, Beatriz; Bianchini, Paolo; Diaspro, Alberto; Iagatti, Alessandro; Patrizi, Barbara; Foggi, Paolo; Abbruzzetti, Stefania; Viappiani, Cristiano (Scientific Reports. Vol.5, 15564 (2015), 2015-10)Antibacterial treatments based on photosensitized production of reactive oxygen species is a promising approach to address local microbial infections. Given the small size of bacterial cells, identification ... -
Tetramethylbenzidine: an acoustogenic photoacoustic probe for reactive oxygen species detection
Nonell, Santi; Agut Bonsfills, Montserrat; Bresolí Obach, Roger; Frattini, Marcello; Abbruzzetti, Stefania; Viappiani, Cristiano (Sensors. Vol.20, n.20 (2020), 5952, 2020-10)Photoacoustic imaging is attracting a great deal of interest owing to its distinct advantages over other imaging techniques such as fluorescence or magnetic resonance image. The availability of photoacoustic ... -
Tuning the local solvent composition at a drug carrier surface: the effect of dimethyl sulfoxide/water mixture on the photofunctional properties of hypericin–β-lactoglobulin complexes
Nonell, Santi; Rodríguez Amigo, Beatriz; Agut Bonsfills, Montserrat; Delcanale, Pietro; Juárez Jiménez, Jordi; Luque, F. Javier; Abbruzzetti, Stefania; Viappiani, Cristiano (Journal of Materials Chemistry B. Vol.5, n.8 (2017), p.1633-1641, 2017-01)Aggregation is a major problem for the anti-microbial photodynamic applications of hydrophobic photosensitizers since it strongly reduces the amount of singlet oxygen generated in aqueous solutions. ... -
Versatile Supramolecular Complex for Targeted Antimicrobial Photodynamic Inactivation
Mussini, Andrea; Uriati, Eleonora; Hally, Cormac; Nonell, Santi; Bianchini, Paolo; Diaspro, Alberto; Pongolini, Stefano; Delcanale, Pietro; Abbruzzetti, Stefania; Viappiani, Cristiano (Bioconjugate Chemistry 2022, 33(4), 666–676, 2022-04-20)We report the development of a supramolecular structure endowed with photosensitizing properties and targeting capability for antimicrobial photodynamic inactivation. Our synthetic strategy uses the ...