Browsing by Author "Agut Bonsfills, Montserrat"
Now showing items 1-17 of 17
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A comparative study on two cationic porphycenes: photophysical and antimicrobial photoinactivation evaluation
Nonell, Santi; Agut Bonsfills, Montserrat; Ruiz González, Rubén; Reddi, Elena (International Journal of Molecular Sciences. Vol.16, n.11 (2015), p.27072-27086, 2015-11)Over the last decades, the number of pathogenic multi-resistant microorganisms has grown dramatically, which has stimulated the search for novel strategies to combat antimicrobial resistance. Antimicrobial ... -
A Double Payload Complex between Hypericin and All-trans Retinoic Acid in the β-Lactoglobulin Protein
Rodríguez Amigo, Beatriz; Hally, Cormac; Roig Yanovsky, Núria; Delcanale, Pietro; Abbruzzetti, Stefania; Agut Bonsfills, Montserrat; Viappiani, Cristiano; Nonell, Santi (Antibiotics, 11(2), 2022, 282, 2022)Combined therapies are usually used to treat acne vulgaris since this approach can tackle various foci simultaneously. Using a combination of spectroscopic, computational, and microbiological techniques ... -
Análisis simultáneo de aflatoxinas y ocratoxina A en compost por HPLC-MS
Comellas Riera, Lluís; Agut Bonsfills, Montserrat; Broto Puig, Francesc; Navajas, H. (Afinidad. Vol.66, n.546 (2010), p.94-99, 2010-03)Las aflatoxinas y ocratoxina A son las micotoxinas más estudiadas debido a su elevada toxicidad y amplia distribución. En este trabajo se describe un método de análisis simultáneo de las aflatoxinas ... -
Cluster and Kill: the Use of Clustering-Triggered Emission Materials for Singlet Oxygen Photosensitization in Antimicrobial Photodynamic Therapy
Dueñas Parro, Karina; Gulias, Oscar; Agut Bonsfills, Montserrat; de la Cruz-Martínez, Felipe; Lara Sánchez, Agustín; Castro Osma, José A.; García Reyes, Juan F.; Sánchez Ruiz, Antonio; Martín, Cristina; Nonell, Santi; Bresolí Obach, Roger (Advanced Optical Materials 2025, 13 (3), 2402179, 2025-01-24)The emergence of light-based technologies is revolutionizing modern medicine and healthcare by enabling precise disease diagnosis and treatment through various luminescent agents and imaging techniques. ... -
Concanavalin A Delivers a Photoactive Protein to the Bacterial Wall
Mussini, Andrea; Delcanale, Pietro; Berni, Melissa; Pongolini, Stefano; Jordà-Redondo, Mireia; Agut Bonsfills, Montserrat; Steinbach, Peter J.; Nonell, Santi; Abbruzzetti, Stefania; Viappiani, Cristiano (International Journal of Molecular Sciences. 2024;25(11):5751, 2024-05-25)Modular supramolecular complexes, where different proteins are assembled to gather targeting capability and photofunctional properties within the same structures, are of special interest for bacterial ... -
Effective photodynamic inactivation of 26 Escherichia coli strains with different antibiotic susceptibility profiles: a planktonic and biofilm study
Nonell, Santi; Agut Bonsfills, Montserrat; Gulías Borau, Òscar; McKenzie, Giselle; Bayó, Miquel (Antibiotics. Vol.9, n.3 (2020), 98, 2020-02)The emergence of multidrug-resistant bacteria is a growing problem and alternative therapies are being sought to effectively address this issue. The aim of this study is to assess a range of Escherichia ... -
Estudio de la producción de aflatoxinas B1, G1, B2 y G2 en semillas de anacardo por parte de Aspergillus parasiticus CECT 2681 mediante cromatografía líquida de ultra-alta resolución
Broto Puig, Francesc; Agut Bonsfills, Montserrat; Comellas Riera, Lluís; Alfaro, Claudia Verónica (Afinidad. Vol.70, n.563 (2013), p.170-174, 2013-07)En este trabajo se pone a punto un método de cromatografía líquida de ultra-alta resolución para el análisis de aflatoxinas en semillas de anacardo. El tiempo de análisis cromatográfico para la detección ... -
Evaluación mediante HPLC-MS de la capacidad de producción de aflatoxinas y ocratoxina A por parte de 20 cepas de Aspergillus y Penicillium aisladas de compost
Agut Bonsfills, Montserrat; Comellas Riera, Lluís; Cuadrench-Tripiana, Anna (Afinidad. Vol.71, n.565 (2014), p.14-19, 2014-01)Este artículo aporta los resultados obtenidos tras realizar el aislamiento e identificación de los mohos presentes en muestras obtenidas en los distintos estadios de la producción de compost en dos ... -
Morphology effects on singlet oxygen production and bacterial photoinactivation efficiency by different silica-protoporphyrin IX nanocomposites
Nonell, Santi; Planas, Oriol; Gulías Borau, Òscar; Agut Bonsfills, Montserrat; Zampini, G.; Marmottini, F.; Latterini, L. (RSC Advances. Vol.7, n.24 (2017), p.14422-14429, 2017-03)Different silica-protoporphyrin IX (PpIX) nanocomposites have been synthesized to evaluate the dependence of singlet oxygen production and bacterial inactivation efficiency on the morphology of the ... -
On the mechanism of Candida tropicalis biofilm reduction by the combined action of naturally-occurring anthraquinones and blue light
Nonell, Santi; Bresolí Obach, Roger; Agut Bonsfills, Montserrat; Marioni, Juliana; Comini, Laura R.; Cabrera, José L.; Paraje, María G.; Núñez Montoya, Susana C. (PLoS ONE. Vol.12, n.7 (2017), e0181517, 2017-07)The photoprocesses involved in the photo-induced Candida tropicalis biofilm reduction by two natural anthraquinones (AQs), rubiadin (1) and rubiadin-1-methyl ether (2), were examined. Production of ... -
Photosensitive EGFR-Targeted Nanocarriers for Combined Photodynamic and Local Chemotherapy
de las Heras, Elena; Sagristá, M. Lluïsa; Agut Bonsfills, Montserrat; Nonell, Santi (Pharmaceutics 2022, 14(2), 405, 2022-02)The major limitation of any cancer therapy lies in the difficulty of precisely controlling the localization of the drug in the tumor cells. To improve this drawback, our study explores the use of ... -
Photosensitizing proteins for a targeted antibacterial photodynamic inactivation
Mussini, A.; Hally, C.; Viappiani, C.; Nonell, Santi; Agut Bonsfills, Montserrat (Il Nuovo Cimento C - Colloquia on Physics 2021;44(4-5):122, 2021-08-13)One of the emerging global health threats is the drug-resistant microbial diseases that could cause millions of deaths each year by 2050. A very promising tool to tackle antimicrobial resistance is ... -
Singlet oxygen in antimicrobial photodynamic therapy: photosensitizer-dependent production and decay in E. coli
Nonell, Santi; Agut Bonsfills, Montserrat; Ragàs Amalrich, Xavier; He, Xin; Roxo-Rosa, Mónica; Rocha Gonsalves, António; Serra, Arménio C. (Molecules. Vol.18, n.3 (2013), p.2712-2725, 2013-02)Several families of photosensitizers are currently being scrutinized for antimicrobial photodynamic therapy applications. Differences in physical and photochemical properties can lead to different ... -
Subdiffraction localization of a nanostructured photosensitizer in bacterial cells
Agut Bonsfills, Montserrat; Nonell, Santi; Delcanale, Pietro; Pennacchietti, Francesca; Maestrini, Giulio; Rodríguez Amigo, Beatriz; Bianchini, Paolo; Diaspro, Alberto; Iagatti, Alessandro; Patrizi, Barbara; Foggi, Paolo; Abbruzzetti, Stefania; Viappiani, Cristiano (Scientific Reports. Vol.5, 15564 (2015), 2015-10)Antibacterial treatments based on photosensitized production of reactive oxygen species is a promising approach to address local microbial infections. Given the small size of bacterial cells, identification ... -
Synthesis, photophysical characterization and photoinduced antibacterial activity of methylene blue-loaded amino- and mannose-targeted mesoporous silica nanoparticles
Planas Marquès, Oriol; Bresolí Obach, Roger; Nos, Jaume; Gallavardin, Thibault; Ruiz González, Rubén; Agut Bonsfills, Montserrat; Nonell, Santi (Molecules. Vol.20, n.4 (2015), p.6284-6298, 2015-04)Over the last 20 years, the number of pathogenic multi-resistant microorganisms has grown steadily, which has stimulated the search for new strategies to combat antimicrobial resistance. Antimicrobial ... -
Tetramethylbenzidine: an acoustogenic photoacoustic probe for reactive oxygen species detection
Nonell, Santi; Agut Bonsfills, Montserrat; Bresolí Obach, Roger; Frattini, Marcello; Abbruzzetti, Stefania; Viappiani, Cristiano (Sensors. Vol.20, n.20 (2020), 5952, 2020-10)Photoacoustic imaging is attracting a great deal of interest owing to its distinct advantages over other imaging techniques such as fluorescence or magnetic resonance image. The availability of photoacoustic ... -
Tuning the local solvent composition at a drug carrier surface: the effect of dimethyl sulfoxide/water mixture on the photofunctional properties of hypericin–β-lactoglobulin complexes
Nonell, Santi; Rodríguez Amigo, Beatriz; Agut Bonsfills, Montserrat; Delcanale, Pietro; Juárez Jiménez, Jordi; Luque, F. Javier; Abbruzzetti, Stefania; Viappiani, Cristiano (Journal of Materials Chemistry B. Vol.5, n.8 (2017), p.1633-1641, 2017-01)Aggregation is a major problem for the anti-microbial photodynamic applications of hydrophobic photosensitizers since it strongly reduces the amount of singlet oxygen generated in aqueous solutions. ...