Browsing by Author "Hally, Cormac"
Now showing items 1-5 of 5
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A Double Payload Complex between Hypericin and All-trans Retinoic Acid in the β-Lactoglobulin Protein
Rodríguez Amigo, Beatriz; Hally, Cormac; Roig Yanovsky, Núria; Delcanale, Pietro; Abbruzzetti, Stefania; Agut Bonsfills, Montserrat; Viappiani, Cristiano; Nonell, Santi (Antibiotics, 11(2), 2022, 282, 2022)Combined therapies are usually used to treat acne vulgaris since this approach can tackle various foci simultaneously. Using a combination of spectroscopic, computational, and microbiological techniques ... -
An Ultra-Long-Lived Triplet Excited State in Water at Room Temperature: Insights on the Molecular Design of Tridecafullerenes
Ramos-Soriano, Javier; Pérez-Sánchez, Alfonso; Ramírez-Barroso, Sergio; Beatriz, Illescas; Rodriguez-Fortea, Antonio; Poblet, Josep M.; Hally, Cormac; Nonell, Santi; García-Fresnadillo, David; Rojo, Javier; Martín, Nazario; Azmani, Khalid (Angewandte Chemie International Edition, 2021-05-13)Suitably engineered molecular systems exhibiting triplet excited states with very long lifetimes are important for high-end applications in nonlinear optics, photocatalysis, or biomedicine. We report ... -
Exploring Structure–Activity Relationships in Photodynamic Therapy Anticancer Agents Based on Ir(III)-COUPY Conjugates
Rovira, Anna; Ortega Forte, Enrique; Hally, Cormac; Jordà Redondo, Mireia; Abad-Montero, Diego; Vigueras, Gloria; Martínez, Jesús I.; Bosch, Manel; Nonell, Santi; Ruiz, José; Marchán, Vicente (Journal of Medicinal Chemistry 2023, 66 (12), 2023-06-22)Photodynamic therapy holds great promise as a non-invasive anticancer tool against drug-resistant cancers. However, highly effective, non-toxic, and reliable photosensitizers with operability under ... -
Photosensitizing proteins for antibacterial photodynamic inactivation
Nonell, Santi; Hally, Cormac; Delcanale, Pietro; Viappiani, Cristiano; Abbruzzetti, Stefania (Translational Biophotonics. Vol.2, n.1-2 (2020) e201900031, 2020-05)We review recent applications of water‐soluble proteins as carriers for photosensitizing molecules in antimicrobial photodynamic therapy (aPDT). The low water solubility of photosensitizers and their ... -
Versatile Supramolecular Complex for Targeted Antimicrobial Photodynamic Inactivation
Mussini, Andrea; Uriati, Eleonora; Hally, Cormac; Nonell, Santi; Bianchini, Paolo; Diaspro, Alberto; Pongolini, Stefano; Delcanale, Pietro; Abbruzzetti, Stefania; Viappiani, Cristiano (Bioconjugate Chemistry 2022, 33(4), 666–676, 2022-04-20)We report the development of a supramolecular structure endowed with photosensitizing properties and targeting capability for antimicrobial photodynamic inactivation. Our synthetic strategy uses the ...