Browsing by Author "Delcanale, Pietro"

Now showing items 1-6 of 6

    • A Double Payload Complex between Hypericin and All-trans Retinoic Acid in the β-Lactoglobulin Protein 

      Rodríguez Amigo, Beatriz; Hally, Cormac; Roig Yanovsky, Núria; Delcanale, Pietro; Abbruzzetti, Stefania; Agut Bonsfills, Montserrat; Viappiani, Cristiano; Nonell, Santi (Antibiotics, 11(2), 2022, 282, 2022)
      Combined therapies are usually used to treat acne vulgaris since this approach can tackle various foci simultaneously. Using a combination of spectroscopic, computational, and microbiological techniques ...

    • Concanavalin A Delivers a Photoactive Protein to the Bacterial Wall 

      Mussini, Andrea; Delcanale, Pietro; Berni, Melissa; Pongolini, Stefano; Agut Bonsfills, Montserrat; Steinbach, Peter J.; Nonell, Santi; Abbruzzetti, Stefania; Viappiani, Cristiano (International Journal of Molecular Sciences. 2024;25(11):5751, 2024-05-25)
      Modular supramolecular complexes, where different proteins are assembled to gather targeting capability and photofunctional properties within the same structures, are of special interest for bacterial ...

    • Photosensitizing proteins for antibacterial photodynamic inactivation 

      Nonell, Santi; Hally, Cormac; Delcanale, Pietro; Viappiani, Cristiano; Abbruzzetti, Stefania (Translational Biophotonics. Vol.2, n.1-2 (2020) e201900031, 2020-05)
      We review recent applications of water‐soluble proteins as carriers for photosensitizing molecules in antimicrobial photodynamic therapy (aPDT). The low water solubility of photosensitizers and their ...

    • Subdiffraction localization of a nanostructured photosensitizer in bacterial cells 

      Agut Bonsfills, Montserrat; Nonell, Santi; Delcanale, Pietro; Pennacchietti, Francesca; Maestrini, Giulio; Rodríguez Amigo, Beatriz; Bianchini, Paolo; Diaspro, Alberto; Iagatti, Alessandro; Patrizi, Barbara; Foggi, Paolo; Abbruzzetti, Stefania; Viappiani, Cristiano (Scientific Reports. Vol.5, 15564 (2015), 2015-10)
      Antibacterial treatments based on photosensitized production of reactive oxygen species is a promising approach to address local microbial infections. Given the small size of bacterial cells, identification ...

    • Tuning the local solvent composition at a drug carrier surface: the effect of dimethyl sulfoxide/water mixture on the photofunctional properties of hypericin–β-lactoglobulin complexes 

      Nonell, Santi; Rodríguez Amigo, Beatriz; Agut Bonsfills, Montserrat; Delcanale, Pietro; Juárez Jiménez, Jordi; Luque, F. Javier; Abbruzzetti, Stefania; Viappiani, Cristiano (Journal of Materials Chemistry B. Vol.5, n.8 (2017), p.1633-1641, 2017-01)
      Aggregation is a major problem for the anti-microbial photodynamic applications of hydrophobic photosensitizers since it strongly reduces the amount of singlet oxygen generated in aqueous solutions. ...

    • Versatile Supramolecular Complex for Targeted Antimicrobial Photodynamic Inactivation 

      Mussini, Andrea; Uriati, Eleonora; Hally, Cormac; Nonell, Santi; Bianchini, Paolo; Diaspro, Alberto; Pongolini, Stefano; Delcanale, Pietro; Abbruzzetti, Stefania; Viappiani, Cristiano (Bioconjugate Chemistry 2022, 33(4), 666–676, 2022-04-20)
      We report the development of a supramolecular structure endowed with photosensitizing properties and targeting capability for antimicrobial photodynamic inactivation. Our synthetic strategy uses the ...